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Full-Text Articles in Chemistry

Development Of Bifunctional Lysophosphatidic Acid & Lysophosphatidylcholine Activity Probes To Characterize Their Specific Binding Protein Receptors, Ritu Nandal Aug 2011

Development Of Bifunctional Lysophosphatidic Acid & Lysophosphatidylcholine Activity Probes To Characterize Their Specific Binding Protein Receptors, Ritu Nandal

Masters Theses

Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) activity has been found to be dysregulated in cancer cells and therefore is a crucial target for research. Only a few LPA receptors have been identified to date, namely LPA 1, LPA 2, LPA 3, LPA 4 and peroxisome proliferator-activated receptors (PPAR). In order to identify receptors, we are designing and synthesizing bifunctional LPA and LPC activity probes to characterize their protein targets using activity based protein profiling (ABPP) among other proteomic technologies. By synthesizing bifunctional signaling probes that can mimic the naturally occurring LPA and LPC molecules and selectively capture receptors by virtue …


Examination Of 4he Droplets And Droplets Containing Impurities At Zero Kelvin Using A Density Functional Approach, Ellen Brown Aug 2011

Examination Of 4he Droplets And Droplets Containing Impurities At Zero Kelvin Using A Density Functional Approach, Ellen Brown

Masters Theses

Abstract

Detailed in this manuscript is a methodology to model ground state properties of 4He droplets at zero pressure and zero Kelvin using a density functional theory of liquid helium. The density functional approach examined here consists of two noted functionals from the literature and corresponding mean field definitions. A mean field and trial density are defined for each system and optimized to self-consistency using a matrix diagonalization technique. Initial calculations of planar slabs are performed and demonstrate reasonable agreement with experiment and with prior studies using density functional theory. Quantum properties of droplets and droplets containing atomic dopants …


Non-Thermal Plasma Inactivation Of Bacillus Amyloliquefaciens Spores, Yaohua Huang Aug 2011

Non-Thermal Plasma Inactivation Of Bacillus Amyloliquefaciens Spores, Yaohua Huang

Masters Theses

Bacterial spores have remarkable resistance to a variety of harsh conditions, causing spoilage in food industry and becoming the primary bacterial agent in biowarfare and bioterrorism. In this study, inactivation mechanisms of Bacillus amyloliquefaciens (BA) spores by non-thermal plasma (NTP) were investigated by using Fourier-transform infrared spectroscopy (FTIR) as a major tool to exam spores after NTP treatment. Chemometric techniques, such as multivariate classification models based on soft independent modeling of Class Analogy (SIMCA) and Principal Component Analysis (PCA), were employed to identify functional group changes in FTIR spectra. The IR absorbance bands correlated to dipicolinic acid (DPA) decreased after …


The Effect Of Surface Hydrophobicity On Wind Erosion Probed By Atomic Force Microscopy, Bradley Eric Frost Jan 2011

The Effect Of Surface Hydrophobicity On Wind Erosion Probed By Atomic Force Microscopy, Bradley Eric Frost

Masters Theses

No abstract provided.


Catalytic Activity Of Titania And Titania-Containing Nanomaterials: And, Spatial Distribution Of Silica Surface Groups Using A Tethered Amine Catalyst, Ramkumar Samala Jan 2011

Catalytic Activity Of Titania And Titania-Containing Nanomaterials: And, Spatial Distribution Of Silica Surface Groups Using A Tethered Amine Catalyst, Ramkumar Samala

Masters Theses

No abstract provided.


Relaxation Imaging To Characterize Lightweight Polymer-Crosslinked Aerogels, Emmalou T. Satterfield Jan 2011

Relaxation Imaging To Characterize Lightweight Polymer-Crosslinked Aerogels, Emmalou T. Satterfield

Masters Theses

"Silica aerogels are three-dimensional assemblies of silica nanoparticles with extremely low densities. In some instances, the internal void volume is more than 90% of the total volume. The highly porous structure of the aerogels leads to attractive properties for thermal and noise insulation, due to very low thermal conductivity and very high acoustic impedance. The strength of silica aerogels has been substantially improved by casting a thin conformal polymer coating over the entire internal porous surfaces of the nanostructure. The coating reinforces the interparticle connections without significantly compromising the internal void space. To analyze and compare the properties of several …


The Affect Of Surface Hydrophobicity On Wind Erosion Probed By Atomic Force Microscopy, Bradley Eric Frost Jan 2011

The Affect Of Surface Hydrophobicity On Wind Erosion Probed By Atomic Force Microscopy, Bradley Eric Frost

Masters Theses

No abstract provided.


Structural And Photochemical Behavior Of Phenyl And Dihydrophenyl Sulfonamidecinnamic Acids, Sergey Zinovchik Jan 2011

Structural And Photochemical Behavior Of Phenyl And Dihydrophenyl Sulfonamidecinnamic Acids, Sergey Zinovchik

Masters Theses

No abstract provided.


Method Developments To Analyze Caffeine And Acesulfame-K Concentrations In Natural Waters In And Around Charleston, Il, Usa, Laleen Bodhipaksha Jan 2011

Method Developments To Analyze Caffeine And Acesulfame-K Concentrations In Natural Waters In And Around Charleston, Il, Usa, Laleen Bodhipaksha

Masters Theses

No abstract provided.


Synthesis Of Molecular Containers Based On Modifications Of Resorcin(4)Arene And Calix(4)Arene, Anupama Makineni Jan 2011

Synthesis Of Molecular Containers Based On Modifications Of Resorcin(4)Arene And Calix(4)Arene, Anupama Makineni

Masters Theses

No abstract provided.