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Full-Text Articles in Chemistry

Use Of Boron Compounds To Precipitate Uranium From Water, David A. Atwood Sep 2008

Use Of Boron Compounds To Precipitate Uranium From Water, David A. Atwood

Chemistry Faculty Patents

A method is provided for removing uranium from water. The method includes the mixing of a boron reagent with water contaminated with uranyl dication ions, leading to removal of the uranium from that water.


Tetrahymena Thermophila And Candida Albicans Group I Intron-Derived Ribozymes Can Catalyze The Trans-Excision-Splicing Reaction, P. Patrick Dotson Ii, Ashley K. Johnson, Stephen M. Testa Sep 2008

Tetrahymena Thermophila And Candida Albicans Group I Intron-Derived Ribozymes Can Catalyze The Trans-Excision-Splicing Reaction, P. Patrick Dotson Ii, Ashley K. Johnson, Stephen M. Testa

Chemistry Faculty Publications

Group I intron-derived ribozymes can catalyze a variety of non-native reactions. For the trans-excision-splicing (TES) reaction, an intron-derived ribozyme from the opportunistic pathogen Pneumocystis carinii catalyzes the excision of a predefined region from within an RNA substrate with subsequent ligation of the flanking regions. To establish TES as a general ribozyme-mediated reaction, intron-derived ribozymes from Tetrahymena thermophila and Candida albicans, which are similar to but not the same as that from Pneumocystis, were investigated for their propensity to catalyze the TES reaction. We now report that the Tetrahymena and Candida ribozymes can catalyze the excision of a …


Inversion Symmetry And Local Vs. Dispersive Interactions In The Nucleation Of Hydrogen Bonded Cyclic N-Mer And Tape Of Imidazolecarboxamidines, Sihui Long, Venkatraj Muthusamy, Peter G. Willis, Sean Parkin, Arthur Cammers Jul 2008

Inversion Symmetry And Local Vs. Dispersive Interactions In The Nucleation Of Hydrogen Bonded Cyclic N-Mer And Tape Of Imidazolecarboxamidines, Sihui Long, Venkatraj Muthusamy, Peter G. Willis, Sean Parkin, Arthur Cammers

Chemistry Faculty Publications

Substitutional changes to imidazolecarboxamidine that preserved intermolecular hydrogen bonding in the solid state were used to study the relationship between packing and the hydrogen bond motif. Various motifs competed, but the most common imidazolecarboxamidine crystalline phase was a Ci symmetric dimer that established inversion centers by associating enantiomeric tautomers. Counter to intuition, the calculated gas-phase energies per molecule of the solid state atomic coordinates of the Ci dimer motifs were higher than those of the C1 dimer, trimer, tetramer and tape motifs, while the packing densities of Ci dimers were found to be higher. This result …


Silylethynylated Heteroacenes And Electronic Devices Made Therewith, John E. Anthony, Marcia M. Payne, Susan A. Odom, Sean Parkin Jun 2008

Silylethynylated Heteroacenes And Electronic Devices Made Therewith, John E. Anthony, Marcia M. Payne, Susan A. Odom, Sean Parkin

Chemistry Faculty Patents

Novel silylethynylated heteroacenes and electronic devices made with those compounds are disclosed.


Aequorin And Obelin Mutants With Differing Wavelengths And Bioluminescence, Sylvia Daunert, Sapna K. Deo, Emre Dikici, Laura Rowe Mar 2008

Aequorin And Obelin Mutants With Differing Wavelengths And Bioluminescence, Sylvia Daunert, Sapna K. Deo, Emre Dikici, Laura Rowe

Chemistry Faculty Patents

The invention relates to aequorin and obelin mutants whose emission is shifted with respect to wild type. The shift in emission is accomplished using a combination of mutations of amino acids within aequorin or obelin that affect bioluminescence; use of different types of chromophores, i.e., coelenterazines with variable emission characteristics; and modifications of the photoprotein with fluorophores that will allow for emission of light at longer wavelengths as a result of energy transfer. Additionally, an assay employing aequorin mutants to test for HIV-1 protease inhibitors is disclosed.