Chemistry Commons^™

Carborane Functionalized Cysteine : Synthesis, Structural Characterization, And Biological Evaluation For Boron Neutron Capture Therapy, Tianyu He

Legacy Theses & Dissertations (2009 - 2024)

Carbon-containing boranes, also known as carboranes, have attracted immense interest since their discovery in the 1950’s. Characterization of carboranes revealed their highly symmetrical polyhedral structures, which make them chemically and thermally stable. Their unique chemical properties, hydrophobicity and aromaticity also make them ideal candidates for a variety of applications. Prominent among these are the applications in materials and medicinal chemistry. On the materials chemistry front, carboranes have been investigated as self-assembly building blocks, liquid crystals and gas storage and separation materials. In the medicinal chemistry field, carborane derivatives have been extensively investigated as potential drugs, with a lot of attention …