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Full-Text Articles in Chemistry
Analysis Of Copper(Ii) Using The Ascorbate/Oxygen System – A Valuable Undergraduate Resource, Sean Tobin, John Cassidy, Kevin Kurian, Tony Betts
Analysis Of Copper(Ii) Using The Ascorbate/Oxygen System – A Valuable Undergraduate Resource, Sean Tobin, John Cassidy, Kevin Kurian, Tony Betts
Articles
In deionised water, ascorbic acid (AH−), through oxidation by oxygen in the presence of copper(II), was found to degrade with zero-order kinetics. The magnitude of the reaction rate varied directly with the copper(II) concentration. At a higher pH (7.4), the same reaction was found to be pseudo-first order. Once again, the magnitude of the rate increased linearly with copper(II) concentration at a micromolar level. Dissolved oxygen levels, in excess AH− and trace copper(II), displayed similar kinetics under both conditions. Monitoring of either AH− levels or dissolved oxygen concentration was found to be a useful novel undergraduate practical laboratory for trace …
Improving Extraction Processes Of Crustacean Chitin Using Solid State Analytical Techniques, Fionn O'Fearghail, Michelle Giltrap, Christine O'Connor, Patrice Behan
Improving Extraction Processes Of Crustacean Chitin Using Solid State Analytical Techniques, Fionn O'Fearghail, Michelle Giltrap, Christine O'Connor, Patrice Behan
Articles
Solid state analytical techniques are becoming more widely used for the analysis of a range of organic products which demonstrate very poor solubility in both common organic and polar solvents and as such cannot be accurately characterised using solution based techniques. Primarily used as a secondary technique for qualitative analysis of insoluble intermediates and products in organic synthesis, 13C CP-MAS NMR can be utilised in tandem with a targeted extraction and clean up procedure for accurate quantitative analysis of insoluble bio-molecules of interest. Here solid state 13C CP-MAS NMR is utilised as the primary analytical technique in the characterisation of …
An Analysis Of Drug Dissolution In Vivo, David Mcdonnell
An Analysis Of Drug Dissolution In Vivo, David Mcdonnell
Doctoral
The testing of drug dissolution rates from solid dosage forms is a very important area of research within the pharmaceutical industry. The ability to produce drugs with a given dissolution rate will lead to improved performance in the treatment of patients and will be of economic benefit to the pharmaceutical industry. However, dissolution testing in laboratories, aimed at reflecting in-vivo conditions, can be both time consuming and costly. Currently, most simulations of drug dissolution take place in standardized USP (United States Pharmaceutical) apparatuses. A number of these apparatuses exist, and it is the aim of this thesis to analyse drug …