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TÜBİTAK

2022

Antimicrobial activity

Articles 1 - 4 of 4

Full-Text Articles in Chemistry

Thio-Schiff Bases Derived From 2,2'-Disulfanedianiline Via Nanocerium Oxide: Antimicrobial Effect And Antiproliferative Effects In Melanoma Cells, Aslihan Dalmaz, Sefa Durmuş, Görkem Dülger, Merve Alpay Jan 2022

Thio-Schiff Bases Derived From 2,2'-Disulfanedianiline Via Nanocerium Oxide: Antimicrobial Effect And Antiproliferative Effects In Melanoma Cells, Aslihan Dalmaz, Sefa Durmuş, Görkem Dülger, Merve Alpay

Turkish Journal of Chemistry

In this study, the synthesis of dimeric disulfide-Schiff bases was carried out using two methods. The structures of the obtained Schiff bases were elucidated by various spectroscopic methods as well as elemental analysis. The Schiff base derivative compounds (3a-6) were screened for in vitro antibacterial activity against multidrug-resistant microorganisms using microdilution method. All the tested compounds showed varying inhibition zones against the pathogens. According to MIC results, the compound 2 was shown strong inhibitory activity against all the tested microorganisms compared to antibiotics. In addition, all the tested compounds showed different antiproliferative effects on the melanoma cell line (B16F10). Our …


Major Chemical Constituents From Illicium Griffithii Hook. F. & Thoms Of North East India And Their Cytotoxicity And Antimicrobial Activities, Deepjyoti Dutta, Bardwi Narzary, Snigdha Saikia, Kashyap J. Tamuli, Manobjyoti Bordoloi, Neipihoi Lhouvum, Shyamalendu Nath, Ranjan K. Sahoo, Barnali Gogoi, Surovi Saikia, Nayan K. Bhattacharyya Jan 2022

Major Chemical Constituents From Illicium Griffithii Hook. F. & Thoms Of North East India And Their Cytotoxicity And Antimicrobial Activities, Deepjyoti Dutta, Bardwi Narzary, Snigdha Saikia, Kashyap J. Tamuli, Manobjyoti Bordoloi, Neipihoi Lhouvum, Shyamalendu Nath, Ranjan K. Sahoo, Barnali Gogoi, Surovi Saikia, Nayan K. Bhattacharyya

Turkish Journal of Chemistry

Illicium griffithii Hook. f. & Thoms is an endemic medicinal plant of North East India found in the Eastern Himalayan region of biodiversity mega centre. Herein, chemical investigation of I. griffithii, afforded five compounds and their structures were determined through extensive use of NMR, HRMS, and FT-IR spectroscopy. The complete proton-proton, proton-carbon coupling network of compound 1 was determined using 1H-1H COSY, HSQC and NOESY NMR experiments. All the compounds were evaluated for their cytotoxic activity by MTT assay and antimicrobial activity by Agar well diffusion method. Compound 1 exhibited significant cytotoxicity activity against Lung cancer (A549) and pancreatic …


Synthesis, Characterization, And Antimicrobial Evaluation Of Polyvinylalcohol-Osthol Composite Films, Ishrat Gowsia, Feroz Mir, Javid Banday Jan 2022

Synthesis, Characterization, And Antimicrobial Evaluation Of Polyvinylalcohol-Osthol Composite Films, Ishrat Gowsia, Feroz Mir, Javid Banday

Turkish Journal of Chemistry

Although poly-vinyl alcohol (PVA) has certain mechanical drawbacks such as a weak barrier, it has widely been used in food packaging over the last many years. To increase the suitability of PVA (C2H4O)n and render it ideal for food packaging, a diversity of studies have already been carried out. In the below-mentioned script, we, for the first time, report the use of natural product osthol in making a new composite with PVA for enhancing thermal, physicochemical, and antimicrobial properties. The significant aim of the report is the insertion of osthol (C15H16O3 …


Cyclotide-Rich Fractions Containing Nanofibers By Electrospinning: Preparation, Characterization And Examination Of Antimicrobial Activity, Eli̇f Büşra Baş, Cemi̇l Kürekci̇, Orhan Murat Kalfa, Muharrem Akcan Jan 2022

Cyclotide-Rich Fractions Containing Nanofibers By Electrospinning: Preparation, Characterization And Examination Of Antimicrobial Activity, Eli̇f Büşra Baş, Cemi̇l Kürekci̇, Orhan Murat Kalfa, Muharrem Akcan

Turkish Journal of Chemistry

In this study, antimicrobial nanofibers were produced with the mixtures of polyvinyl alcohol (PVA) and cyclotide-rich fractions by electrospinning method. After extraction, the first separation was carried out with C18 flash chromatography and then fractioned into five separate parts by reversed-phase high-pressure liquid chromatography (RP-HPLC). The molecular weights of cyclotides in each fraction were determined by quadrupole time-of-flight liquid chromatography-mass spectrometry (Q-TOF LC-MS). Cyclotide-rich fractions were mixed with 10% of PVA solution and nanofibers were produced from this biocomposite mixture by electrospinning method. The nanofibers were characterized by field emission scanning electron microscopy (FE-SEM), and it was observed that 100% …