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Flavonoid Constituents Of Sideritis Caesarea, Belkis Halfon, Ece Çi̇ftçi̇, Gülaçti Topçu
Flavonoid Constituents Of Sideritis Caesarea, Belkis Halfon, Ece Çi̇ftçi̇, Gülaçti Topçu
Turkish Journal of Chemistry
The acetone extract of the aerial parts of Sideritis caesarea Duman, Aytaç & Başer (Lamiaceae) afforded the flavonoids penduletin (1) and apigenin (2) and 6 glycosylated flavonoids, 4'-O-methyl-isoscutellarein-7-O-[6'''-O-acetyl-\beta-D-allopyranosyl- (1 \to 2)]-6\"-O-acetyl-\beta -D-glucopyranoside (3), 4'-O-methylhypolaetin- 7-O-[6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]-6\"-O-acetyl-\beta- D-glucopyranoside (4), isoscutellarein-7-O-[6'''-O-acetyl-\beta- D-allopyranosyl-(1 \to 2)]-6\"-O-acetyl-\beta -D-glucopyranoside (5), isoscutellarein-7-O-[6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]- \beta-D-glucopyranoside (6), 4'-O-methylhypolaetin-7-O- [6'''-O-acetyl-\beta -D-allopyranosyl-(1 \to 2)]-\beta-D- glucopyranoside (7), and hypolaetin-7-O-[6'''-O-acetyl-\beta- D-allopyranosyl-(1 \to 2)]-\beta -D-glucopyranoside (8). The compounds were identified by the use of 1D- and 2D-NMR and UV spectroscopic techniques and by comparisons with the reported data. The acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of the acetone, methanol, …
Terpenoids, Essential Oil Composition, Fatty Acid Profile, And Biological Activities Of Anatolian Salvia Fruticosa Mill., Gülaçti Topçu, Mehmet Öztürk, Tuba Kuşman, Ayşe Asli Barla Demi̇rkoz, Ufuk Kolak, Ayhan Ulubelen
Terpenoids, Essential Oil Composition, Fatty Acid Profile, And Biological Activities Of Anatolian Salvia Fruticosa Mill., Gülaçti Topçu, Mehmet Öztürk, Tuba Kuşman, Ayşe Asli Barla Demi̇rkoz, Ufuk Kolak, Ayhan Ulubelen
Turkish Journal of Chemistry
The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., afforded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids (\alpha -amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and a flavone (salvigenin). The galls (apples) of the collected plant were separately extracted with hexane to afford fatty acids composed mainly of oleic acid (29\%), palmitoleic acid (29\%), and stearic acid (23.20\%), which exhibited high anticholinesterase activity, particularly against BChE. The essential oil, obtained from the aerial parts of the plant, exhibited high AChE inhibitory …