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Full-Text Articles in Chemistry
Analysis Of Novel Cyanide Antidote Dimethyl Trisulfide For Pharmacokinetic Studies, And Sulfur Mustard Metabolites For Identification Of Biomarker Of Inhaled Dose, Erica Manandhar
Electronic Theses and Dissertations
Cyanide poisoning by accidental or intentional exposure poses a severe health risk. The current FDA approved antidotes for cyanide poisoning can be effective, but each suffers from specific major limitations. Dimethyl trisulfide (DMTS), a sulfur donor that detoxifies cyanide by converting it into thiocyanate, is a promising next generation cyanide antidote. Although a validated analytical method to analyze DMTS is not currently available from any matrix, one will be vital for the approval of DMTS as a therapeutic agent against cyanide poisoning. Hence, a stir bar sorptive extraction (SBSE) gas chromatography – mass spectrometry (GC-MS) method was developed and validated …
Ice Concentration Linked With Extractive Stirrer (Icecles), Nujud Omar Maslamani
Ice Concentration Linked With Extractive Stirrer (Icecles), Nujud Omar Maslamani
Electronic Theses and Dissertations
Clean water is very important for human health. Therefore, drinking water contamination is a significant research concern, especially with the increasing global population. Some contaminants, such as pesticides, can cause health effects even at low levels. Therefore, trace and ultratrace analysis of contaminants in drinking water is essential. Ultratrace analysis typically requires highly effective sample preparation methods and/or highly sensitive instruments. There are currently advanced sample preparations techniques available to analytical chemists that may allow trace analysis of certain analytes. These include liquid-liquid extraction (LLE), solid phase extraction (SPE), solid phase micro extraction (SPME), and stir bar sorpitive extraction (SBSE). …