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Full-Text Articles in Chemistry
The Effect Of Metabolic Modulators On The Rate Of Steady State Water Exchange In S. Cerevisiae Grown In Chemostat Bioreactors, Samantha Mumford, Mark Woods, Johnathan Dutra
The Effect Of Metabolic Modulators On The Rate Of Steady State Water Exchange In S. Cerevisiae Grown In Chemostat Bioreactors, Samantha Mumford, Mark Woods, Johnathan Dutra
Student Research Symposium
Water transport across the lipid bilayer due to osmotic stress causes a change in intracellular volume over time. At isotonic equilibrium there is no change in cell volume and yet water exchange does not stop. Water molecules continue to exchange rapidly with those of the extracellular space. The rate constant for steady state water efflux (kio) can be measured using contrast enhanced magnetic resonance (MR) and the two-site exchange (2SX) model. kio is known to correlate with the cellular energy molecule ATP making it a probable biomarker for metabolic diseases such as cancer. Measurements of k …