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Articles 1 - 2 of 2
Full-Text Articles in Chemistry
Investigating Paraben 3,5-Substitution Effects On Estrogen Receptor Binding, Zachary Morgan
Investigating Paraben 3,5-Substitution Effects On Estrogen Receptor Binding, Zachary Morgan
Longwood Senior Theses
Paraben, a compound formerly found in cosmetics, has been found to bind the Estrogen Receptor Alpha (ERα), a receptor found primarily in reproductive tissues. In paraben binding the ERα, the risk of breast cancer increases. In order to better understand how 3,5-substituted paraben derivatives bind the ER, Molecular Operating Environment was used to calculate the interaction energy associated with binding these substrates to the ER. It was found that substituted paraben molecules exhibit a weaker binding to the ER, whereas paraben molecules with varying alkyl chains bind stronger to the ER. Further, in comparing molecular and bimolecular docking data, it …
Volume 11, Jacob Carney, Ryan White, Joseph Hyman, Jenny Raven, Megan Garrett, Ibrahim Kante, Summer Meinhard, Lauren Johnson, William "Editha" Dean Howells, Laura Gottschalk, Christopher Siefke, Pink Powell, Natasha Woodmancy, Katharine Colley, Abbey Mays, Charlotte Potts
Volume 11, Jacob Carney, Ryan White, Joseph Hyman, Jenny Raven, Megan Garrett, Ibrahim Kante, Summer Meinhard, Lauren Johnson, William "Editha" Dean Howells, Laura Gottschalk, Christopher Siefke, Pink Powell, Natasha Woodmancy, Katharine Colley, Abbey Mays, Charlotte Potts
Incite: The Journal of Undergraduate Scholarship
Table of Contents:
Introduction, Dr. Roger A. Byrne, Dean
From the Editor, Dr. Larissa "Kat" Tracy
From the Designers, Rachel English, Rachel Hanson
Synthesis of 3,5-substituted Parabens and their Antimicrobial Properties, Jacob Coarney, Ryan White
Chernobyl: Putting "Perestroika" and "Glasnot" to the Test, Joseph Hyman
Art by Jenny Raven
Watering Down Accessibility: The Issue with Public Access to Alaska's Federal Waterways, Meagan Garrett
Why Has the Democratic Republic of the Congo outsourced its Responsibility to Educate its Citizens? Ibrahim Kante
Art by Summer Meinhard
A Computational Study of Single Molecule Diodes, Lauren Johnson
Satire of …