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Full-Text Articles in Chemistry

World Bank -Cpa Conflict: The Struggle To Define Human Rights And Development In The Philippines, Adam B. Robbins Jan 2007

World Bank -Cpa Conflict: The Struggle To Define Human Rights And Development In The Philippines, Adam B. Robbins

Honors Theses

This thesis analyzes the interactions between the World Bank (hereafter, the Bank) and the Cordillera Peoples Alliance (CPA), an indigenous and environmental advocacy group based in the Cordillera region of Luzon, in the Philippines. Using data gathered through both text-based and participatory research methods, I analyze the discursive relationship and violent confrontations between the two organizations. Conflicting development and human rights values cause the majority of these conflicts. I focus on how each organization enacts development and human rights, and how this leads to conflict. Ultimately, I intend for this thesis to offer practical guidance for the reader involved in …


Cisplatin Interstrand Cross-Linking Of Defined Sequence Nucleosomal Dna, Erin Elizabeth Wilkes Jan 2000

Cisplatin Interstrand Cross-Linking Of Defined Sequence Nucleosomal Dna, Erin Elizabeth Wilkes

Honors Theses

DNA interstrand cross-linking agents have been recognized for many years to be powerful antitumor chemotherapeutics. While the interactions between free DNA and many anticancer drugs have been explored extensively, there is less infonnation available about these interactions with nucleosomal DNA. Nitrogen mustards have been reported to exhibit relatively similar cross-linking sites and efficiencies of binding in free and nucleosomal DNA, but mitomycin C exhibits markedly reduced cross-linking near the center of nucleosomal DNA. This current study focuses on cisplatin interstrand cross-linking of the 154 base pair 55 rRNA gene fragment of Xenopus borealis reconstituted with histones from chicken erythrocytes. The …