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Full-Text Articles in Chemistry
Characterization Of Drawn And Undrawn Poly-L-Lactide Films By Differential Scanning Calorimetry, John F. Turner Ii, A. Riga, Anne O'Connor, Jing Zhang, Jennifer Collis
Characterization Of Drawn And Undrawn Poly-L-Lactide Films By Differential Scanning Calorimetry, John F. Turner Ii, A. Riga, Anne O'Connor, Jing Zhang, Jennifer Collis
Chemistry Faculty Publications
Poly-L-lactic acid (PLLA) is an optically active, biocompatible and biodegradable polymer that has been widely investigated as an artificial cell scaffold material. In its most crystalline form, PLLA is highly anisotropic and is one of the most piezoelectric polymers known. Conversely, amorphous PLLA exhibits little, if any, piezoelectric behavior. Compression molded PLLA films can be endowed with varying amounts of crystalline character and piezoelectricity by uniaxially stretching the polymer in a hot air bath. Understanding the precise crystalline architecture of PLLA that results from tensile drawing is important for constructing cell scaffolds that have highly tailored biodegradation and cell guiding …
Determination Of Crystalline Content Gradients In Cold-Drawn Poly-L-Lactic Acid Films By Dsc, Anne O'Connor, A. Riga, John F. Turner Ii
Determination Of Crystalline Content Gradients In Cold-Drawn Poly-L-Lactic Acid Films By Dsc, Anne O'Connor, A. Riga, John F. Turner Ii
Chemistry Faculty Publications
Poly-L-lactic acid (PLLA) is a semi-crystalline, optically active, biodegradable, and biocompatible polymer that has been utilized extensively in biomedical applications as an implantable artificial cell scaffold material. In its crystalline form, PLLA is piezoelectric and it has been implicated in the enhancement of electromechanically induced osteogenesis in vivo. In its amorphous state, however, PLLA does not exhibit piezoelectricity. By uniaxially cold-drawing the polymer, PLLA can be endowed with varying degrees of piezoelectricity. It is important to understand the crystalline architecture of drawn PLLA so that the osteogenic potential imparted by piezoelectricity, if any, can be differentiated from the effects of …