Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Chemistry
Enabling Method To Design Versatile Biomaterial Systems From Colloidal Building Blocks, Shalini Saxena, L. Andrew Lyon
Enabling Method To Design Versatile Biomaterial Systems From Colloidal Building Blocks, Shalini Saxena, L. Andrew Lyon
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Development of materials with fine spatial control over topographical, mechanical, or chemical features has been investigated for a variety of applications. Here we present a method to fabricate an array of polyelectrolyte constructs including two-dimensionally and three-dimensionally patterned assemblies using both compressible and incompressible colloidal building blocks. This method eliminates prior constraints associated with specific chemistries, and can be used to develop modular, multi-component, patterned assemblies. In particular, development of constructs were investigated using microgels, which are colloidally stable hydrogel microparticles, polystyrene (PS) beads, and PS-microgel core-shell building blocks in conjunction with the polycation poly(ethyleneimine) (PEI). The topography, mechanical properties, …
Bulk Modulus Of Poly(N-Isopropylacrylamide) Microgels Through The Swelling Transition, B. Sierra-Martin, Y. Laporte, A. B. South, L. Andrew Lyon, A. Fernandez-Nieves
Bulk Modulus Of Poly(N-Isopropylacrylamide) Microgels Through The Swelling Transition, B. Sierra-Martin, Y. Laporte, A. B. South, L. Andrew Lyon, A. Fernandez-Nieves
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
We report measurements of the bulk modulus of individual poly(N-isopropylacrylamide) microgels along their swelling transition. The modulus is determined by measuring the volume deformation of the microgel as a function of osmotic pressure using dextran solutions. We find that the modulus softens through the transition, displaying a nonmonotonous behavior with temperature. This feature is correctly reproduced by the theory of Flory for polymer gels, once the concentration dependence of the solvency parameter is properly incorporated.