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Full-Text Articles in Chemistry

Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi Mar 2021

Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi

Arkansas Women in STEM Conference

Herein, we describe a carrier-free combination nanodrug for treatment of cancer. In this work, we combined a photothermal compound and a chemotherapeutic drug using ionic liquid chemistry. We utilized a facile, one-step metathesis approach to replace the counter cation of a near infra-red (NIR) dye (photothermal agent) with a chemotherapeutic cation to synthesize an ionic material-based combination cancer therapy drug to deliver multiple mechanisms simultaneously. The nanodrugs were developed by using a reprecipitation method. The detailed photophysical properties of this new combination therapy molecule was investigated in ethanol solution as well as in nanoparticles forms in aqueous media. The singlet …


Nanomedicine, Mark Tuominen Jan 2015

Nanomedicine, Mark Tuominen

Nanotechnology Teacher Summer Institutes

An overview of nanomedicine. The end goal of nanomedicine is improved diagnostics, treatment and prevention of disease. Nanotechnology holds key to a number of recent and future breakthroughs in medicine.