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Full-Text Articles in Chemistry
Resonance Raman Studies Of Oxygenated Forms Of Myoglobin And Cyp2b4 And Their Mutants, Ying Wang
Resonance Raman Studies Of Oxygenated Forms Of Myoglobin And Cyp2b4 And Their Mutants, Ying Wang
Dissertations (1934 -)
Important oxidative heme enzymes use hydrogen peroxide or activate molecular oxygen to generate highly reactive peroxo-, hydroperoxo- and feryl intermediates resulting from heterolytic O-O bond cleavage. Members of the cytochrome P450 superfamily catalyze difficult chemical transformations, including hydroxylations and C-C bond cleavage reactions. In mammals, these enzymes function to reliably produce important steroids with the required high degree of structural precision. On the other hand, certain other mammalian P450s serve a different role, efficiently metabolizing xenobiotics, including pharmaceuticals and environmental pollutants. Though so important, the precise mechanisms involved in such transformations are incompletely understood, because of difficulties in structurally characterizing …
Electrocatalytic Activities Of Mb/Aunps/Mwnts/Gc Electrode For Hydrogen Peroxide Reduction, Zheng-Juan Huang, Hua-Ping Peng, Dai-Jun Cha, Ai-Lin Liu, Wei Chen, Xin-Hua Lin, Yong-Ji You
Electrocatalytic Activities Of Mb/Aunps/Mwnts/Gc Electrode For Hydrogen Peroxide Reduction, Zheng-Juan Huang, Hua-Ping Peng, Dai-Jun Cha, Ai-Lin Liu, Wei Chen, Xin-Hua Lin, Yong-Ji You
Journal of Electrochemistry
A novel matrix, multiwalled carbon nanotubes supported Au nanoparticles composite nanomaterial (AuNPs/MWNTs), for immobilization of protein and biosensing was designed using a simple and effective one-step in situ synthesis route. Using myoglobin (Mb) as a model, the direct electrochemistry of the immobilized proteins on the AuNPs/MWNTs composite was studied. The results showed that the AuNPs/MWNTs composite can maintain the bioactivity and facilitate the direct electrochemistry of Mb in the Mb/AuNPs/MWNTs/GC electrode. Based on the direct electron transfer of the immobilized Mb, the protein electrode exhibited excellent electrocatalytic activity to the reduction of H2O2 with a linear range …
Study Of Electrochemical Behaviour Of Myoglobin Using Cyclic Voltammetry And Synchronous Fluorescence Spectroscopy, Ju Chou, Haihong Zhou, Tianhong Lu, Yue Wu
Study Of Electrochemical Behaviour Of Myoglobin Using Cyclic Voltammetry And Synchronous Fluorescence Spectroscopy, Ju Chou, Haihong Zhou, Tianhong Lu, Yue Wu
Journal of Electrochemistry
Myoglobin undergoes irreversible heterogeneous electron transfer reactions at bare metal electroeds. Thus, much effort has been devoted to obtain quasi-reversible electrochemical reactions of myoglobin at metal electrodes modified with mediators￣(1～3). However, the electron transfer rates at the above modified electrodes is very small so that the spectroelectrochemical techniques should be used in the most of studies. Recently, Taniguchi et al￣[4]. reported that a quasi-reversible electrochemical reaction of the purified horse heart myoglobin was observed at an indium oxide electrode with cyclic voltammetry technique. It was suggested that high purification of myoglobin may be the main reason for obtaining a quasi-reversible …