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Articles 1 - 4 of 4
Full-Text Articles in Chemistry
Enhancing Vanadium Redox Battery Performance Using Tungsten-Bismuth-Based Oxide Nanostructures As Electrode Modifiers, Taher Al Najjar
Enhancing Vanadium Redox Battery Performance Using Tungsten-Bismuth-Based Oxide Nanostructures As Electrode Modifiers, Taher Al Najjar
Theses and Dissertations
Renewable energy power plants require high efficiency conversion and storage systems that can store high amounts of energy and can be integrated with the electrical grid. Vanadium redox flow batteries are very promising for this application. However, one major drawback of VRFBs is their low power density which means that right now they cannot replace non-renewable energy sources. Different carbon materials are used as electrodes in VRFBs and each carbon material affects the battery’s performance in a different way. Modification of these electrodes can increase the power density of the battery. Some metal oxides like tungsten oxide can enhance vanadium …
In Vitro And In Vivo Identification And Quantification Of Carmofur And 5-Fluorouracil Using Tandem Mass Spectrometry, Mohammad Mohiminul Islam
In Vitro And In Vivo Identification And Quantification Of Carmofur And 5-Fluorouracil Using Tandem Mass Spectrometry, Mohammad Mohiminul Islam
Theses and Dissertations
Glioblastoma is the most aggressive solid tumor of the brain. Prior studies from our lab found that carmofur, also known as 1-hexylcarbanoyl 5-fluorouracil (HCFU) is a promising candidate in suppressing and killing tumor cell lines compared to the FDA-approved drug temozolomide. Originally developed as pro-drug of 5-fluorouracil (5-FU), carmofur has been in use in clinic for the treatment of colorectal cancer for over four decades in Japan. Having it used in clinics, it has a high probability of repurposing for diseases with no cure such as glioblastoma. Carmofur has also been found effective against other cancers such as head and …
Antiviral Effects Of Metalloshielding: Differential Antiviral Activity Of Polynuclear Platinum And Cobalt Compounds, Mary Zoepfl
Antiviral Effects Of Metalloshielding: Differential Antiviral Activity Of Polynuclear Platinum And Cobalt Compounds, Mary Zoepfl
Theses and Dissertations
The majority of antiviral drug development has focused on virus-specific discovery targeting discrete steps in the individual life cycles. Although great strides have been made for a number of clinically relevant diseases such as human immunodeficiency virus, influenza virus, and hepatitis B, broad spectrum antivirals do not exist. Broad spectrum antivirals would offer (1) treatment for viruses without specifically-targeted antivirals, (2) treatment for viruses which have developed resistance to their available treatments, and (3) a rapidly deployable treatment option in viral epidemics. Many viruses including human cytomegalovirus (HCMV), HIV, and SARS-CoV-2. rely on heparan sulfate (HS), a highly sulfated glycosaminoglycan …
Behavioral Screening And Chiral Bioanalysis Of Emerging Stimulant-Type Drugs In Rats, Tyson R. Baird
Behavioral Screening And Chiral Bioanalysis Of Emerging Stimulant-Type Drugs In Rats, Tyson R. Baird
Theses and Dissertations
The epidemic of drug use in the United States and elsewhere in the world has resulted in tragic loss of life and substantial economic costs. Novel psychoactive substances (NPS) are one of the contributors to this problem, and the lack of information about many of these drugs compounds their risk. This dissertation proposes a strategy to use intracranial self-stimulation (ICSS) as a behavioral screening tool to assess emerging drugs of abuse for their abuse potential in order to generate a proactive threat assessment. A series of stimulant-type drugs including methcathinone, α-pyrrolidinohexanophenone (α-PHP), cocaine, and the phenyltropane analogs of cocaine WIN35428 …