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Chemistry Commons

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Medicinal-Pharmaceutical Chemistry

University of Nebraska - Lincoln

1999

Articles 1 - 2 of 2

Full-Text Articles in Chemistry

Method Of Storing Active Zero Valent Zinc Metal, Reuben D. Rieke Oct 1999

Method Of Storing Active Zero Valent Zinc Metal, Reuben D. Rieke

Chemistry Department: Faculty Publications

A novel Zerovalent Zinc species and an organozinc reagent are disclosed. The Zerovalent Zinc species is directly pro duced by reaction of a reducing agent on a Zinc Salt, preferably Zn(CN). The organozinc regent results from the reaction of the Zerovalent Zinc species and an organic compound having one or more stable anionic leaving groups. These organozinc reagents include a wide spectrum of functional groups in the organic radical, and are useful in a variety of reactions Schemes.


Affinity Chromatography: A Review Of Clinical Applications, David S. Hage Jan 1999

Affinity Chromatography: A Review Of Clinical Applications, David S. Hage

David Hage Publications

Affinity chromatography is a type of liquid chromatography that makes use of biological-like interactions for the separation and specific analysis of sample components. This review describes the basic principles of affinity chromatography and examines its use in the testing of clinical samples, with an emphasis on HPLCbased methods. Some traditional applications of this approach include the use of boronate, lectin, protein A or protein G, and immunoaffinity supports for the direct quantification of solutes. Newer techniques that use antibody-based columns for on- or off-line sample extraction are examined in detail, as are methods that use affinity chromatography in combination with …