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Full-Text Articles in Chemistry

Combination Nanomedicines For Cancer Therapy, Noureen Siraj Mar 2024

Combination Nanomedicines For Cancer Therapy, Noureen Siraj

Arkansas Women in STEM Conference

Nanomedicines derived from combination ionic nanomaterials (INMs) offer synergistic therapy for effective treatment of cancer. This approach addresses the limitations of conventional treatment options and offers active targeting of tumors due to EPR effect


Surface Area Enhancement Of Doped Carbon Materials Via Novel Freeze-Pore Methodology, Iris Denmark Mar 2022

Surface Area Enhancement Of Doped Carbon Materials Via Novel Freeze-Pore Methodology, Iris Denmark

Arkansas Women in STEM Conference

Supercapacitors are one of today’s growing means of alternative energy. They are portable, produce much higher capacitance than traditional capacitors, and operate under lower voltages than that of batteries. Herein, we have synthesized a series of supercapacitor materials from sodium lignosulfonate, otherwise known as lignosol, which are co-doped with phosphorus and nitrogen. The materials are synthesized utilizing a green and time-efficient microwave irradiation process. Subsequently, these materials have been optimized by utilizing a novel process by which surface area and electrochemical properties is enhanced by freezing of their porous surface. Materials undergoing this method have shown significant increase in BET …


Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi Mar 2021

Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi

Arkansas Women in STEM Conference

Herein, we describe a carrier-free combination nanodrug for treatment of cancer. In this work, we combined a photothermal compound and a chemotherapeutic drug using ionic liquid chemistry. We utilized a facile, one-step metathesis approach to replace the counter cation of a near infra-red (NIR) dye (photothermal agent) with a chemotherapeutic cation to synthesize an ionic material-based combination cancer therapy drug to deliver multiple mechanisms simultaneously. The nanodrugs were developed by using a reprecipitation method. The detailed photophysical properties of this new combination therapy molecule was investigated in ethanol solution as well as in nanoparticles forms in aqueous media. The singlet …