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Full-Text Articles in Chemistry
Tau Kinetics In Alzheimer's Disease, Daniel B. Hier, Sima Azizi, Matthew S. Thimgan, Donald C. Wunsch
Tau Kinetics In Alzheimer's Disease, Daniel B. Hier, Sima Azizi, Matthew S. Thimgan, Donald C. Wunsch
Chemistry Faculty Research & Creative Works
The Cytoskeletal Protein Tau is Implicated in the Pathogenesis of Alzheimer's Disease Which is Characterized by Intra-Neuronal Neurofibrillary Tangles Containing Abnormally Phosphorylated Insoluble Tau. Levels of Soluble Tau Are Elevated in the Brain, the CSF, and the Plasma of Patients with Alzheimer's Disease. to Better Understand the Causes of These Elevated Levels of Tau, We Propose a Three-Compartment Kinetic Model (Brain, CSF, and Plasma). the Model Assumes that the Synthesis of Tau Follows Zero-Order Kinetics (Uncorrelated with Compartmental Tau Levels) and that the Release, Absorption, and Clearance of Tau is Governed by First-Order Kinetics (Linearly Related to Compartmental Tau Levels). …
Polyaniline Nanofiber-Based Gas Sensors, Zhe-Fei Li, Frank D. Blum, Massimo F. Bertino, Chang-Soo Kim
Polyaniline Nanofiber-Based Gas Sensors, Zhe-Fei Li, Frank D. Blum, Massimo F. Bertino, Chang-Soo Kim
Chemistry Faculty Research & Creative Works
There has been recent interest in conducting polymers that have very promising chemical and electrical applications. Some of these polymers have shown great potential for use in sensors.1 Polyaniline is one particular example of a prospective material. In our laboratory, we have studied the synthesis of polyaniline nanofibers. We have carried out one-pot syntheses to obtain polyaniline nanofibers in aqueous solutions where the polymerization was influenced by γ-radiation2 or UV-radiation.3 This polymer can also be patterned with an appropriate photo mask. In our present report, polyaniline nanofiber thin film sensors have been fabricated in one step by employing UV-irradiation and …