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Affinity Of Cadmium Versus Zinc For The Carbonic Anhydrase Active Site, Rachel Phan
Affinity Of Cadmium Versus Zinc For The Carbonic Anhydrase Active Site, Rachel Phan
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Cadmium is a heavy metal found in tobacco plants, nickel-cadmium batteries, and as a byproduct of metal mining. The similarities between the properties of zinc ions and cadmium ions in proteins due to their 2+ charges may cause displacement of zinc by cadmium if encountered and has been shown to do so in several transcription factors. Cadmium’s ability to replace zinc- a metal found in around 3,000 human proteins- is a cause for concern, especially due to its toxicity, long half-life in the body, and larger size.
Carbonic anhydrase is an important metalloprotein protein that relies on a central zinc(II) …