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Full-Text Articles in Chemistry

Raman Spectroscopic Examination Of Bloodstains For Forensic Purposes : Background And Race Determination, Ewelina M. Mistek May 2019

Raman Spectroscopic Examination Of Bloodstains For Forensic Purposes : Background And Race Determination, Ewelina M. Mistek

Legacy Theses & Dissertations (2009 - 2024)

Chapter 1 of this thesis critically overviews recent developments in forensic trace evidence analysis since 2016. It covers improvements to existing techniques as well as new methods for the analysis of fibers, hair, paint, glass, gunshot residue (GSR), and explosives.


Nmr Metabolomics Protocols For Drug Discovery, Fatema Bhinderwala, Robert Powers Jan 2019

Nmr Metabolomics Protocols For Drug Discovery, Fatema Bhinderwala, Robert Powers

Chemistry Department: Faculty Publications

Drug discovery is an extremely difficult and challenging endeavor with a very high failure rate. The task of identifying a drug that is safe, selective and effective is a daunting proposition because disease biology is complex and highly variable across patients. Metabolomics enables the discovery of disease biomarkers, which provides insights into the molecular and metabolic basis of disease and may be used to assess treatment prognosis and outcome. In this regard, metabolomics has evolved to become an important component of the drug discovery process to resolve efficacy and toxicity issues, and as a tool for precision medicine. A detailed …


Characterizing Body Fluids With Raman Spectroscopy : Towards Real World Application, Marisia Ann Fikiet Jan 2019

Characterizing Body Fluids With Raman Spectroscopy : Towards Real World Application, Marisia Ann Fikiet

Legacy Theses & Dissertations (2009 - 2024)

This project continues the research on a new method of body fluid identification and furthers its field capabilities. This method of identification uses Raman spectroscopy and advanced chemometrics to distinguish between body fluids. It is an improvement on current methods because it is confirmatory, non-destructive, and has simple sample preparation. The first objective of this research is to create a model for differentiating body fluids for a new desktop instrument. It was determined that due to resolution differences from a research grade instrument, a new model needed to be made for this the desktop instrument. This model will be able …