Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Chemistry
Measuring The Properties Of Rod-Shaped Bacteria By Single-Entity Electrochemistry, Ashley Tubbs
Measuring The Properties Of Rod-Shaped Bacteria By Single-Entity Electrochemistry, Ashley Tubbs
Theses and Dissertations
Antibiotic-resistant bacteria pose a significant and escalating threat to hospitals around the world, necessitating the development of rapid and sensitive detection methods. Single-entity electrochemistry has emerged as a promising approach for detecting and identifying such bacteria, and monitoring the efficacy of antibiotics in real-time. Herein, we employ the translational diffusion equation for circular cylinders to predict the collision frequency of rod-shaped bacteria, informing our experimental setup. Our work demonstrates that lab-fabricated Pt ultramicroelectrodes can sensitively detect bacteria at femtomolar concentrations under migration-controlled conditions. Further, we present a method implemented in MatLab to automate the analysis of step-like signals observed in …