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Analytical Chemistry

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Selected Works

2012

Articles 1 - 6 of 6

Full-Text Articles in Chemistry

Nontargeted Comprehensive Two-Dimensional Gas Chromatography/Time-Of-Flight Mass Spectrometry Method And Software For Inventorying Persistent And Bioaccumulative Contaminants In Marine Environments, Eunha Hoh, Nathan G. Dodder, Steven J. Lehotay, Kristin C. Pangallo, Christopher M. Reddy, Keith A. Maruya Aug 2012

Nontargeted Comprehensive Two-Dimensional Gas Chromatography/Time-Of-Flight Mass Spectrometry Method And Software For Inventorying Persistent And Bioaccumulative Contaminants In Marine Environments, Eunha Hoh, Nathan G. Dodder, Steven J. Lehotay, Kristin C. Pangallo, Christopher M. Reddy, Keith A. Maruya

Kristin Pangallo

Analytical methods for contaminant monitoring are generally targeted; i.e., they measure defined lists of compounds. Routine monitoring projects using targeted methods are not usually designed to screen for unrecognized or novel contaminants, and therefore miss compounds within the region or population of study that cause, or have the potential to cause, adverse biological impacts. We describe a non-targeted analytical method utilizing direct sample introduction (DSI) coupled to comprehensive two-dimensional gas chromatography with time-offlight mass spectrometry (GC×GC/TOF-MS). To test the capabilities of this instrumental method within the context of marine contaminant surveys, we characterized a broad array of non-polar, persistent and …

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Small Heat Shock Protein Activity Is Regulated By Variable Oligomeric Substructure, J. L. Benesch, M. Ayoub, C. V. Robinson, J. A. Aquilina Jul 2012

Small Heat Shock Protein Activity Is Regulated By Variable Oligomeric Substructure, J. L. Benesch, M. Ayoub, C. V. Robinson, J. A. Aquilina

J. A. Aquilina

The alpha-crystallins are members of the small heat shock protein (sHSP) family of molecular chaperones which have evolved to minimize intracellular protein aggregation, however they are also implicated in a number of protein deposition diseases. In this study we have employed novel mass spectrometry techniques to investigate the changes in quaternary structure associated with this switch from chaperone to adjuvant of aggregation. We have replicated the oligomeric rearrangements observed for in vivo disease-related modifications, without altering the protein sequence, by refolding the alpha-crystallins in vitro. This refolding results in a loss of dimeric substructure concomitant with an augmentation of substrate …

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Vaporization And Sublimation Enthalpies Of Acetanilide And Several Derivatives By Correlation Gas Chromatography, Patamaporn Umnahanant, James Chickos Apr 2012

Vaporization And Sublimation Enthalpies Of Acetanilide And Several Derivatives By Correlation Gas Chromatography, Patamaporn Umnahanant, James Chickos

James Chickos

No abstract provided.

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An Examination Of The Thermodynamics Of Fusion, Vaporization, And Sublimation Of (R,S)- And (R)-Flurbiprofen By Correlation Gas Chromatography, Patamaporn Umnahanant, Darrell Hasty, James Chickos Jan 2012

An Examination Of The Thermodynamics Of Fusion, Vaporization, And Sublimation Of (R,S)- And (R)-Flurbiprofen By Correlation Gas Chromatography, Patamaporn Umnahanant, Darrell Hasty, James Chickos

James Chickos

No abstract provided.

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Selective Recognition Of H2po4 By A Cholestane-Imidazole-Zinc Ensemble, Jyoti Ramesh Jadhav, Md Wasi Ahmad, Hong Seok Kim Dec 2011

Selective Recognition Of H2po4 By A Cholestane-Imidazole-Zinc Ensemble, Jyoti Ramesh Jadhav, Md Wasi Ahmad, Hong Seok Kim

Dr. Mohammad Wasi Ahmad (Md Wasi Ahmad)

A new facile amphiphile cholestane-based zinc complex 4 containing a 3-aminopropylimidazole moiety at the 3a and 7a positions of cholestane was designed and synthesized. Recognition selectivity of the new receptor 4 with various anions was assessed by 1H NMR titration. Dihydrogen phosphate showed the highest binding affinity among all the tested anions

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Development Of Spectrophotometric Method For The Determination Of Perindopril Erbumine In Pharmaceutical Formulations Using 2, 4 Dinitrofluorobenzene, Habibur Rahman Dr. Dec 2011

Development Of Spectrophotometric Method For The Determination Of Perindopril Erbumine In Pharmaceutical Formulations Using 2, 4 Dinitrofluorobenzene, Habibur Rahman Dr.

Habibur Rahman

No abstract provided.

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