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Full-Text Articles in Other Applied Mathematics
Triple Non-Negative Matrix Factorization Technique For Sentiment Analysis And Topic Modeling, Alexander A. Waggoner
Triple Non-Negative Matrix Factorization Technique For Sentiment Analysis And Topic Modeling, Alexander A. Waggoner
CMC Senior Theses
Topic modeling refers to the process of algorithmically sorting documents into categories based on some common relationship between the documents. This common relationship between the documents is considered the “topic” of the documents. Sentiment analysis refers to the process of algorithmically sorting a document into a positive or negative category depending whether this document expresses a positive or negative opinion on its respective topic. In this paper, I consider the open problem of document classification into a topic category, as well as a sentiment category. This has a direct application to the retail industry where companies may want to scour …
Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri
Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri
Theses and Dissertations
miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …