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Applied Mathematics Commons

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Full-Text Articles in Applied Mathematics

How To Extend Interval Arithmetic So That Inverse And Division Are Always Defined, Tahea Hossain, Jonathan Rivera, Yash Sharma, Vladik Kreinovich May 2021

How To Extend Interval Arithmetic So That Inverse And Division Are Always Defined, Tahea Hossain, Jonathan Rivera, Yash Sharma, Vladik Kreinovich

Departmental Technical Reports (CS)

In many real-life data processing situations, we only know the values of the inputs with interval uncertainty. In such situations, it is necessary to take this interval uncertainty into account when processing data. Most existing methods for dealing with interval uncertainty are based on interval arithmetic, i.e., on the formulas that describe the range of possible values of the result of an arithmetic operation when the inputs are known with interval uncertainty. For most arithmetic operations, this range is also an interval, but for division, the range is sometimes a disjoint union of two semi-infinite intervals. It is therefore desirable …


Gene Selection And Classification In High-Throughput Biological Data With Integrated Machine Learning Algorithms And Bioinformatics Approaches, Abhijeet R Patil May 2021

Gene Selection And Classification In High-Throughput Biological Data With Integrated Machine Learning Algorithms And Bioinformatics Approaches, Abhijeet R Patil

Open Access Theses & Dissertations

With the rise of high throughput technologies in biomedical research, large volumes of expression profiling, methylation profiling, and RNA-sequencing data are being generated. These high-dimensional data have large number of features with small number of samples, a characteristic called the "curse of dimensionality." The selection of optimal features, which largely affects the performance of classification algorithms in machine learning models, has led to challenging problems in bioinformatics analyses of such high-dimensional datasets. In this work, I focus on the design of two-stage frameworks of feature selection and classification and their applications in multiple sets of colorectal cancer data. The first …