Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Applied Mathematics
Boundary Homogenization And Capture Time Distributions Of Semipermeable Membranes With Periodic Patterns Of Reactive Sites, Andrew J. Bernoff, Daniel Schmidt, Alan E. Lindsay
Boundary Homogenization And Capture Time Distributions Of Semipermeable Membranes With Periodic Patterns Of Reactive Sites, Andrew J. Bernoff, Daniel Schmidt, Alan E. Lindsay
All HMC Faculty Publications and Research
We consider the capture dynamics of a particle undergoing a random walk in a half- space bounded by a plane with a periodic pattern of absorbing pores. In particular, we numerically measure and asymptotically characterize the distribution of capture times. Numerically we develop a kinetic Monte Carlo (KMC) method that exploits exact solutions to create an efficient particle- based simulation of the capture time that deals with the infinite half-space exactly and has a run time that is independent of how far from the pores one begins. Past researchers have proposed homogenizing the surface boundary conditions, replacing the reflecting (Neumann) …
Numerical Approximation Of Diffusive Capture Rates By Planar And Spherical Surfaces With Absorbing Pores, Andrew J. Bernoff, Alan E. Lindsay
Numerical Approximation Of Diffusive Capture Rates By Planar And Spherical Surfaces With Absorbing Pores, Andrew J. Bernoff, Alan E. Lindsay
All HMC Faculty Publications and Research
In 1977 Berg and Purcell published a landmark paper entitled Physics of Chemore- ception, which examined how a bacterium can sense a chemical attractant in the fluid surrounding it [H. C. Berg and E. M. Purcell, Biophys J, 20 (1977), pp. 193–219]. At small scales the attrac- tant molecules move by Brownian motion and diffusive processes dominate. This example is the archetype of diffusive signaling problems where an agent moves via a random walk until it either strikes or eludes a target. Berg and Purcell modeled the target as a sphere with a set of small circular targets (pores) that …