Applied Mathematics Commons^™

Unique Signed Minimal Wiring Diagrams And The Stanley-Reisner Correspondence, Vanessa Newsome-Slade

Master's Theses

Biological systems are commonly represented using networks consisting of interactions between various elements in the system. Reverse engineering, a method of mathematical modeling, is used to recover how the elements in the biological network are connected. These connections are encoded using wiring diagrams, which are directed graphs that describe how elements in a network affect one another. A signed wiring diagram provides additional information about the interactions between elements relating to activation and inhibition. Due to cost concerns, it is optimal to gain insight into biological networks with as few experiments and data as possible. Minimal wiring diagrams identify the …