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Applied Mathematics Commons

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Full-Text Articles in Applied Mathematics

Complex Valued Graphs For Soft Computing, Florentin Smarandache, W.B. Vasantha Kandasamy, Ilanthenral K Jan 2017

Complex Valued Graphs For Soft Computing, Florentin Smarandache, W.B. Vasantha Kandasamy, Ilanthenral K

Branch Mathematics and Statistics Faculty and Staff Publications

In this book authors for the first time introduce in a systematic way the notion of complex valued graphs, strong complex valued graphs and complex neutrosophic valued graphs. Several interesting properties are defined, described and developed. Most of the conjectures which are open in case of usual graphs continue to be open problems in case of both complex valued graphs and strong complex valued graphs. We also give some applications of them in soft computing and social networks. At this juncture it is pertinent to keep on record that Dr. Tohru Nitta was the pioneer to use complex valued graphs …


Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri Jan 2017

Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri

Theses and Dissertations

miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …