Applied Mathematics Commons^™

Analytic Solutions For Diffusion On Path Graphs And Its Application To The Modeling Of The Evolution Of Electrically Indiscernible Conformational States Of Lysenin, K. Summer Ware

Boise State University Theses and Dissertations

Memory is traditionally thought of as a biological function of the brain. In recent years, however, researchers have found that some stimuli-responsive molecules exhibit memory-like behavior manifested as history-dependent hysteresis in response to external excitations. One example is lysenin, a pore-forming toxin found naturally in the coelomic fluid of the common earthworm Eisenia fetida. When reconstituted into a bilayer lipid membrane, this unassuming toxin undergoes conformational changes in response to applied voltages. However, lysenin is able to "remember" past history by adjusting its conformational state based not only on the amplitude of the stimulus but also on its previous …

Bivariate Markov Chain Model Of Irritable Bowel Syndrome (Ibs) Subtypes And Abdominal Pain, Ricardo Reyna Jr.

Theses and Dissertations

Researchers use stochastic models like continuous-time Markov chains (CTMC) to model progression of morbidities of public health impact, like HIV and Hepatitis C. Most of the research in that area is done for a single disease. In this research, we use a bivariate continuous-time Markov chain (CTMC) to model progression of co-morbidities. In particular, we use a bivariate CTMC to model the joint progression of Irritable Bowel Syndrome (IBS) and abdominal pain. Symptoms of IBS are known to change throughout the duration of the disorder. Hence, patients are normally asked to make a journal of the stool type, symptoms, and …

Sum Of Cubes Of The First N Integers, Obiamaka L. Agu

Electronic Theses, Projects, and Dissertations

In Calculus we learned that 􏰅Sum^{n}_{k=1} k = [n(n+1)]/2 , that Sum^{􏰅n}_{k=1} k^2 = [n(n+1)(2n+1)]/6 , and that Sum^{n}_{k=1} k^{3} = (n(n+1)/2)^{2}. These formulas are useful when solving for the area below quadratic or cubic function over an interval [a, b]. This tedious process, solving for areas under a quadratic or a cubic, served as motivation for the introduction of Riemman integrals. For the overzealous math student, these steps were replaced by a simpler method of evaluating antiderivatives at the endpoints a and b. From my recollection, a former instructor informed us to do the value of memorizing these formulas. …

Numerical Simulations Of Nonlinear Waves And Their Stability: Stokes Waves And Nonlinear Schroedinger Equation, Anastassiya Semenova

Mathematics & Statistics ETDs

The present work offers an investigation of dynamics and stability of nonlinear waves in Hamiltonian systems. The first part of the manuscript discusses the classical problem of water waves on the surface of an ideal fluid in 2D. We demonstrate how to construct the Stokes waves, and how to apply a continuation method to find waves in close vicinity to the limiting Stokes wave. We provide new insight into the stability of the Stokes waves by identifying previously inaccessible branches of instability in the equations of motion for the fluid. We provide numerical evidence that pairs of unstable eigenvalues of …

From Wave Propagation To Spin Dynamics: Mathematical And Computational Aspects, Oleksii Beznosov

Mathematics & Statistics ETDs

In this work we concentrate on two separate topics which pose certain numerical challenges. The first topic is the spin dynamics of electrons in high-energy circular accelerators. We introduce a stochastic differential equation framework to study spin depolarization and spin equilibrium. This framework allows the mathematical study of known equations and new equations modelling the spin distribution of an electron bunch. A spin distribution is governed by a so-called Bloch equation, which is a linear Fokker-Planck type PDE, in general posed in six dimensions. We propose three approaches to approximate solutions, using analytical and modern numerical techniques. We also present …

Stochastic Delay Differential Equations With Applications In Ecology And Epidemics, Hebatallah Jamil Alsakaji

Dissertations

Mathematical modeling with delay differential equations (DDEs) is widely used for analysis and predictions in various areas of life sciences, such as population dynamics, epidemiology, immunology, physiology, and neural networks. The memory or time-delays, in these models, are related to the duration of certain hidden processes like the stages of the life cycle, the time between infection of a cell and the production of new viruses, the duration of the infectious period, the immune period, and so on. In ordinary differential equations (ODEs), the unknown state and its derivatives are evaluated at the same time instant. In DDEs, however, the …

Methods In Modeling Wildlife Disease From Model Selection To Parameterization With Multi-Scale Data, Ian Mcgahan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The effects of emerging wildlife diseases are global and profound, resulting in loss of human life, economic and agricultural impacts, declines in wildlife populations, and ecological disturbance. The spread of wildlife diseases can be viewed as the result of two simultaneous processes: spatial spread of wildlife populations and disease spread through a population. For many diseases these processes happen at different timescales, which is reflected in available data. These data come in two flavors: high-frequency, high-resolution telemetry data (e.g. GPS collar) and low-frequency, low-resolution presence-absence disease data. The multi-scale nature of these data makes analysis of such systems challenging. Mathematical …

Dictionary-Based Data Generation For Fine-Tuning Bert For Adverbial Paraphrasing Tasks, Mark Anthony Carthon

Theses and Dissertations

Recent advances in natural language processing technology have led to the emergence of

large and deep pre-trained neural networks. The use and focus of these networks are on transfer

learning. More specifically, retraining or fine-tuning such pre-trained networks to achieve state

of the art performance in a variety of challenging natural language processing/understanding

(NLP/NLU) tasks. In this thesis, we focus on identifying paraphrases at the sentence level using

the network Bidirectional Encoder Representations from Transformers (BERT). It is well

understood that in deep learning the volume and quality of training data is a determining factor

of performance. The objective of …

Complete Integrability And Discretization Of Euler Top And Manakov Top, Austin Marstaller

Theses and Dissertations

The Euler top is a completely integrable system with physical system implications and the Manakov top is its four-dimensional extension. We are concerned about their complete integrability and the preservation of this property under a specific discretization known as the Hirota-Kimura Discretization. Surprisingly, it is not guaranteed that under any discretization the conserved quantities are preserved and therefore they must be discovered. In this work we construct the Poisson bracket and Lax pair for each system and provide the Lie algebra background needed to do such such constructions.

Lattice Of Maximal-Primary Ideals In Quadratic Orders, Ryan Bridges

Mathematics & Statistics ETDs

An order is a subring of the ring of integers of an algebraic extension, Peruginelli and Zanardo classified the lattices of orders with prime index inside te ring of integers of quadratic extensions of the rational numbers. The lattices are quite striking and have different layered structure depending on whether the prime is inert, split, or ramified. This thesis considers the orders which have prime power index inside the Gaussian integers. This is a nice generalization of the work of Peruginelli and Zanardo, and succeeds in a few classifications of specific instances of orders derived from inert primes.

"A Comparison Of Variable Selection Methods Using Bootstrap Samples From Environmental Metal Mixture Data", Paul-Yvann Djamen

Mathematics & Statistics ETDs

In this thesis, I studied a newly developed variable selection method SODA, and three customarily used variable selection methods: LASSO, Elastic net, and Random forest for environmental mixture data. The motivating datasets have neuro-developmental status as responses and metal measurements and demographic variables as covariates. The challenges for variable selections include (1) many measured metal concentrations are highly correlated, (2) there are many possible ways of modeling interactions among the metals, (3) the relationships between the outcomes and explanatory variables are possibly nonlinear, (4) the signal to noise ratio in the real data may be low. To compare these methods …

Quantitatively Motivated Model Development Framework: Downstream Analysis Effects Of Normalization Strategies, Jessica M. Rudd

Doctor of Data Science and Analytics Dissertations

Through a review of epistemological frameworks in social sciences, history of frameworks in statistics, as well as the current state of research, we establish that there appears to be no consistent, quantitatively motivated model development framework in data science, and the downstream analysis effects of various modeling choices are not uniformly documented. Examples are provided which illustrate that analytic choices, even if justifiable and statistically valid, have a downstream analysis effect on model results. This study proposes a unified model development framework that allows researchers to make statistically motivated modeling choices within the development pipeline. Additionally, a simulation study is …

Methods Of Uncertainty Quantification For Physical Parameters, Kellin Rumsey

Mathematics & Statistics ETDs

Uncertainty Quantification (UQ) is an umbrella term referring to a broad class of methods which typically involve the combination of computational modeling, experimental data and expert knowledge to study a physical system. A parameter, in the usual statistical sense, is said to be physical if it has a meaningful interpretation with respect to the physical system. Physical parameters can be viewed as inherent properties of a physical process and have a corresponding true value. Statistical inference for physical parameters is a challenging problem in UQ due to the inadequacy of the computer model. In this thesis, we provide a comprehensive …

Assessing The Validity Of Sentiment Analysis Measures Through Polychoric Correlation, Kelli N. Kasper

Mathematics & Statistics ETDs

Sentiment analysis methods extract the attitude of a text via systematic algorithms. To evaluate the validity of common sentiment analysis methods, we use polychoric correlation to compare computer-mediated methods and human-rated analogues. Our main topics of interest are the internal consistency of the raters' scores, the level of consensus among raters, and how well raters' scores correlate with those given by sentiment analysis methods for randomly collected Twitter data.

Our analysis found that there is good validity for methods that measure negative and positive sentiments in short texts, both in terms of inter-rater consistency and when comparing raters to computer-mediated …

An Improved Method For Spectroscopic Quality Classification, Elizabeth G. Mayer

Mathematics & Statistics ETDs

Spectral quality classification is a vital step in data cleaning before the

analysis of magnetic resonance spectroscopy (MRS) data can be done. This

analysis compares five methods of quality classification; three of these are

legacy methods, Maudsley et al. (2006), Zhang et al. (2018), and

Bustillo et al. (2020), and two newly created methods that used a random forests

classifier (RFC) to inform their classifications. We found that the random forest

classifier was the most accurate at predicting spectra quality (balanced

accuracy for RF of 88% vs legacy of 70%, 72%, or 72%). A

Random-Forests-Informed Filtering method (RFIFM) for quality …

A Study Of The Efficacy Of Machine Learning For Diagnosing Obstructive Coronary Artery Disease In Non-Diabetic Patients, Demond Larae Handley

Theses and Dissertations

According to the Centers for Disease Control and Prevention, about 18.2 million adults age 20 and older have Coronary Artery Disease in the United States. Early diagnosis is therefore of crucial importance to help prevent debilitating consequences, and principally death for many patients. In this study we use data containing gene expression values from peripheral blood samples in 198 non-diabetic patients, with the goal of developing an age and sex gene expression model for diagnosis of Coronary Artery Disease. We employ machine learning methods to obtain a classification based on genetic information, age and sex. Our implementation uses feed forward …

An A Posteriori Error Analysis Of Stationary Incompressible Magnetohydrodynamics, Ari E. Rappaport

Mathematics & Statistics ETDs

Adjoint based a posteriori error analysis is a technique to produce exact error repre- sentations for quantities of interests that are functions of the solution of systems of partial differential equations (PDE). The tools used in the analysis consist of duality arguments and compatible residuals. In this thesis we apply a posteriori error anal- ysis to the magnetohydrodynamics (MHD) equations . MHD provides a continuum level description of conducting fluids in the presence of electromagnetic fields. The MHD system is therefore a multi-physics system, capturing both fluid and electro- magnetic effects. Mathematically, The equations of MHD are highly nonlinear and …

Dna Complexes Of One Bond-Edge Type, Andrew Tyler Lavengood-Ryan

Electronic Theses, Projects, and Dissertations

DNA self-assembly is an important tool used in the building of nanostructures and targeted virotherapies. We use tools from graph theory and number theory to encode the biological process of DNA self-assembly. The principal component of this process is to examine collections of branched junction molecules, called pots, and study the types of structures that such pots can realize. In this thesis, we restrict our attention to pots which contain identical cohesive-ends, or a single bond-edge type, and we demonstrate the types and sizes of structures that can be built based on a single characteristic of the pot that is …

A Study Of The Design Of Adaptive Camber Winglets, Justin J. Rosescu

Master's Theses

A numerical study was conducted to determine the effect of changing the camber of a winglet on the efficiency of a wing in two distinct flight conditions. Camber was altered via a simple plain flap deflection in the winglet, which produced a constant camber change over the winglet span. Hinge points were located at 20%, 50% and 80% of the chord and the trailing edge was deflected between -5° and +5°. Analysis was performed using a combination of three-dimensional vortex lattice method and two-dimensional panel method to obtain aerodynamic forces for the entire wing, based on different winglet camber configurations. …

Multilevel Asymptotic Parallel-In-Time Techniques For Temporally Oscillatory Pdes, Nicholas Abel

Mathematics & Statistics ETDs

As the clock speeds of individual processors level off and the amount of parallel resources continue to increase rapidly, further exploitation of parallelism is necessary to improve compute times. For time-dependent differential equations, the serial computation of time-stepping presents a bottleneck, but parallel-in-time integration methods offer a way to compute the solution in parallel along the time domain. Parallel-in-time methods have been successful in achieving speedup when computing solutions for parabolic problems; however, for problems with large hyperbolic terms and no strong diffusivity, parallel-in-time methods have traditionally struggled to offer speedup. While work has been done to understand why parallel-in-time …

A Statistical Analysis Of The Unm Facets Design Identity & Beliefs Survey Data, Clarissa A. Sorensen-Unruh

Mathematics & Statistics ETDs

The NSF-funded FACETS (Formation of Accomplished Chemical Engineers for Transforming Society, NSF Award 1623105) grant aims to transform the undergraduate engineering experience in the Department of Chemical and Biological Engineering at the University of New Mexico to address attrition within engineering majors, especially among underserved populations (Brainard & Carlin, 1998). The UNM FACETS Design Identity & Beliefs survey, an assessment tool used as part of the research of the grant, generated the dataset used in this study. I performed several different statistical analyses on the dataset, including confirmatory factor analysis (CFA), principal component analysis (PCA), and cluster analysis. The …

From Branches To Fibers - Investigating F-Actin Networks With Biochemistry And Mathematical Modeling, Melissa A. Riddle

Senior Honors Projects, 2020-current

F-actin networks have different structures throughout the cell depending on their location or mechanical role. For example, at the leading edge of a migrating cell, F-actin is organized in a region called the lamellipodia as a branched network responsible for pushing the membrane outwards. Behind the lamellipodia is a lamellar actin network where focal adhesions and stress fibers originate, and then within the cell cortex, actin is arranged in a gel-like network. Stress fibers are an important organization of F-actin and how they arise from either the branched lamellipodia network or the gel-like cortex network is poorly understood. Our approach …

Target Control Of Networked Systems, Isaac S. Klickstein

Mechanical Engineering ETDs

The control of complex networks is an emerging field yet it has already garnered interest from across the scientific disciplines, from robotics to sociology. It has quickly been noticed that many of the classical techniques from controls engineering, while applicable, are not as illuminating as they were for single systems of relatively small dimension. Instead, properties borrowed from graph theory provide equivalent but more practical conditions to guarantee controllability, reachability, observability, and other typical properties of interest to the controls engineer when dealing with large networked systems. This manuscript covers three topics investigated in detail by the author: (i) the …

Nonlinear Least Squares 3-D Geolocation Solutions Using Time Differences Of Arrival, Michael V. Bredemann

Mathematics & Statistics ETDs

This thesis uses a geometric approach to derive and solve nonlinear least squares minimization problems to geolocate a signal source in three dimensions using time differences of arrival at multiple sensor locations. There is no restriction on the maximum number of sensors used. Residual errors reach the numerical limits of machine precision. Symmetric sensor orientations are found that prevent closed form solutions of source locations lying within the null space. Maximum uncertainties in relative sensor positions and time difference of arrivals, required to locate a source within a maximum specified error, are found from these results. Examples illustrate potential requirements …

Preparing For The Future: The Effects Of Financial Literacy On Financial Planning For Young Professionals, Tanay Singh

Senior Theses

Purpose – Many people between the age of 20 and 34 have not considered planning financially for the future in any significant capacity and in doing so, they limit their potential savings. The purpose of this study is to examine what financial expectations are for people in the early stages of their career and determine if improving financial literacy and revealing financial realities helps to produce more accurate or realistic expectations. Ultimately, the goal is to better prepare participants in the study for the working world and increased responsibilities outside of the college/university environment by getting them to start thinking …

Evaluating An Ordinal Output Using Data Modeling, Algorithmic Modeling, And Numerical Analysis, Martin Keagan Wynne Brown

Murray State Theses and Dissertations

Data and algorithmic modeling are two different approaches used in predictive analytics. The models discussed from these two approaches include the proportional odds logit model (POLR), the vector generalized linear model (VGLM), the classification and regression tree model (CART), and the random forests model (RF). Patterns in the data were analyzed using trigonometric polynomial approximations and Fast Fourier Transforms. Predictive modeling is used frequently in statistics and data science to find the relationship between the explanatory (input) variables and a response (output) variable. Both approaches prove advantageous in different cases depending on the data set. In our case, the data …

Providing Better Choices: An Exploration Of Solutions In Multi-Objective Optimization And Game Theory Using Variational Analysis, Glenn Matthew Harris

Graduate Research Theses & Dissertations

Multi-objective optimization problems and game theory problems have a wide array of

applications and because of this there are different types of solutions available. This dissertation

explores two areas of optimization and a solution type for each. First, substantial

efficiency (SE) as a type of solution to multi-objective optimization problems that extends

proper efficiency. Secondly, strong Nash equilibria (SNE) as a type of solution to game

theoretic problems that extends Nash equilibria. Substantial efficiency is demonstrated to

be a superior solution to the more rudimentary notion of proper efficiency in solving some

multi-objective financial market and economic problems. Using this …

Spectral Analysis Of Complex Dynamical Systems, Casey Lynn Johnson

CGU Theses & Dissertations

The spectrum of any differential equation or a system of differential equations is related to several important properties about the problem and its subsequent solution. So much information is held within the spectrum of a problem that there is an entire field devoted to it; spectral analysis. In this thesis, we perform spectral analysis on two separate complex dynamical systems. The vibrations along a continuous string or a string with beads on it are the governed by the continuous or discrete wave equation. We derive a small-vibrations model for multi-connected continuous strings that lie in a plane. We show that …

Use Of Kalman Filtering In State And Parameter Estimation Of Diabetes Models, Cassidy Le

HMC Senior Theses

Diabetes continues to affect many lives every year, putting those affected by it at higher risk of serious health issues. Despite many efforts, there currently is no cure for diabetes. Nevertheless, researchers continue to study diabetes in hopes of understanding the disease and how it affects people, creating mathematical models to simulate the onset and progression of diabetes. Recent research by David J. Albers, Matthew E. Levine, Andrew Stuart, Lena Mamykina, Bruce Gluckman, and George Hripcsak¹ has suggested that these models can be furthered through the use of Data Assimilation, a regression method that synchronizes a model with a …

Chase-Escape On Sparse Networks, Emma Sylvie Bernstein

Senior Projects Spring 2020

Chase-escape is a competitive growth process in which prey spread through an environment while being chased and consumed by predators. The environment is typically modeled by a graph—such as a lattice, tree, or clique—and the species by particles competing to occupy sites. It is arguably more natural to study these dynamics in heterogeneous environments. To this end, we consider chase-escape on a canonical sparse random graph called the Erdo ̋s-R ́enyi graph. We show that if prey spreads too slowly then both species quickly die out. On the other hand, if prey spreads fast enough, then coexistence occurs. Concrete bounds …