Applied Mathematics Commons^™

Novel Algorithms And Instrumentation For Vibrational Spectroscopic Methods Of Analysis, Mohamed F. Abdelkader

Chemistry & Biochemistry Theses & Dissertations

Raman spectroscopy is a form of vibrational spectroscopy that has been increasingly applied to qualitative analysis of chemicals, explosives, pharmaceuticals, and fuels due to its non-invasive and non-destructive nature; its ease of sampling; and its high molecular specificity. These characteristics of Raman spectroscopy also facilitate its use for both in-line and at-line analysis. The principle limitation of Raman spectroscopy is optical interference arising from both analyte and non-analyte fluorescence. In this dissertation, a solution to this problem is presented in the form of a novel spectrometer design which operates in a sequentially shifted excitation mode to eliminate fluorescence backgrounds, fixed …