Physical Sciences and Mathematics Commons^™

The Role Of Mannosyl-Phosphoryl-Dihydropolyisoprenol In The Synthesis Of Mammalian Glycoproteins, John W. Baynes, An-Fei Hsu, Edward C. Heath

Faculty Publications

A mouse myeloma tumor was used as a model system to study the biochemical steps involved in the incorporation of mannose into glycoproteins. This tumor, MOPC-46B, synthesizes a K-type immunoglobulin light chain (K-46) which is a glycoprotein with a single oligosaccharide side chain containing mannose as one of its constituent sugars. MOPC-46B microsomal preparations contain enzymes which transfer mannose from the sugar nucleotide, GDPmannose, to endogenous lipid and protein acceptors. Formation of the mannolipid proceeds by the reversible transfer of mannose from GDP-mannose to an endogenous phospholipid. The mannolipid was purified and characterized by chemical methods and mass spectrometry as …

Photochemical Rearrangements Of 6/5 -Fused Cross-Conjugated Cyclohexadiensnes In Protic Solvents, Drury Caine, John T. Gupton, Ko Ming, William J. Powers Iii

Chemistry Faculty Publications

Irradiation of the ring A unsubstituted 6/5-fused cross-conjugated cyclohexadienone (1a) and its 2-methyl derivative (1b) in methanolic acetic acid yields, in addition to other products, novel tricyclononane derivatives which have been assigned the structures (3a) and (3b).

The Preparation And Characterization Of The Palladium(Ii) And Platinum(Ii) Chelates Of Three Cyclic Tertiary Amino Acids., Floyd Michael Hogue

University of the Pacific Theses and Dissertations

The purpose of this study was to prenare and characterize the palladium (II) and platinum (II) chelates of 1-pyrrolidineacetic acid, 1-piperidineacetic acid, and hexahydro-1-azepineacetic acid.

The ligands were prepared by reacting the cyclic secondary arnines (pyrrolidine, piperidine, and hexahydroazepine) with sodium chloroacetate. The resulting cyclic tertiary amino acids were saponified and, finally, converted to the hydrochloride salts by neutralization with hydrochloric acid.

The chelates were prepared by adding 1.0 millimole of K₂PdC1₄ or K₂PtC1₄ to a solution made by dissolving 2.0 Millimoles of amino acid hydrochloride in 25 ml. of water. The pH was …

The Kinetics And Mechanism Of The Reaction Of Chromium(Ii) With Pentaaquodiiodomethyl Chromium(Iii) And Pentaaquomonoiodomethyl Chromium(Iii) Ions., Ronald Sinclair Nohr

University of the Pacific Theses and Dissertations

Transition metal ions, in low oxidation states, have gained increasing use as versatile reducing agents for a number of organic compounds. The ability of metal ion to act as reducing agents in organic reactions is frequently thought to be due to the formation of intermediates which contain an organic species bound to a metal, although the identy of these organo-metallic intermediates has been determined in relatively few cases.

The purpose of this research was to investigate the kinetics and mechanism of one such reaction: the reduction of iodoform to methane by chromium(II). Two air stable organochromium(III) intermediates were separated and …

Formation And Kinetics Of Dissociation Of Some Pentaaquotrihalomethyl Chromium(Iii) Ions., Sher Khan Malik

University of the Pacific Theses and Dissertations

The present.study was an investigation of the formation and kinetic stability of store complexes contain.ir)ing a chromium-carbon bond in an aqueous medium. An orange-brown pentaaquotrifluoromethylchromium(III) ion was obtained by the reduction of trifluororrethyl iodide with Cr(II) and is the most inert of any organochrotnium(III) complex known. The initial aquation rates of trifluoromethylchromium(III) ion were described by the differential rate law -dln [(H₂O)₅CrCF₃²⁺]/dt = k_{o + k1(H⁺)}

The products of the initial reaction were hexaaquochromium (III), carbon monoxide and HF. The values of k_o and k₁ at …