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Articles 1 - 5 of 5
Full-Text Articles in Physical Sciences and Mathematics
A Convenient Synthesis Of 2-Azido And 2-Thiocyanato-2,3-Unsaturated Cyclic Ketones, Mesut Boz, Ömer Zai̇m, Hi̇lal Esen
A Convenient Synthesis Of 2-Azido And 2-Thiocyanato-2,3-Unsaturated Cyclic Ketones, Mesut Boz, Ömer Zai̇m, Hi̇lal Esen
Turkish Journal of Chemistry
2-Azido and 2-thiocyanato-2,3-unsaturated ketones were synthesized by utilizing functionalization of 5- or 6-membered cycloalkane-1,2-diones, namely diosphenols, with dimethylthiocarbomoyl chloride, which activates the system towards reaction with nucleophiles in acidic conditions. Replacement of the enolic oxygen of the diosphenols with azide and thiocyanate may be achieved by treating their dimethylthiocarbamates with sodium azide or potassium thiocyanate in boiling acetonitrile/acetic acid.
An Efficient One Pot Synthesis Of 1,4-Dihydropyridines Using Alumina Sulfuric Acid (Asa) Catalyst, Mustafa Arslan, Cüneyt Faydali, Mustafa Zengi̇n, Mustafa Küçüki̇slamoğlu, Hülya Demi̇rhan
An Efficient One Pot Synthesis Of 1,4-Dihydropyridines Using Alumina Sulfuric Acid (Asa) Catalyst, Mustafa Arslan, Cüneyt Faydali, Mustafa Zengi̇n, Mustafa Küçüki̇slamoğlu, Hülya Demi̇rhan
Turkish Journal of Chemistry
An efficient synthetic method for 1,4-dihydropyridines has been developed using 3 or 4 component condensation reactions of aldehydes, 1,3-dicarbonyl compounds, and ammonium acetate in the presence of alumina sulfuric acid catalyst in minimum methanol at reflux temperature. This procedure offers several advantages including high yields, an environmentally friendly procedure, short reaction times, and a simple work-up procedure.
Synthesis, Characterization, And Optical Properties Of Novel 2,5-Bis[4-(2-(-Arylvinyl)Phenyl]-1,3,4-Oxadiazoles, Dao-Hang He, Yong-Chuang Zhu, Zhuo-Ru Yang, Ai-Xi Hu, Gao Cao
Synthesis, Characterization, And Optical Properties Of Novel 2,5-Bis[4-(2-(-Arylvinyl)Phenyl]-1,3,4-Oxadiazoles, Dao-Hang He, Yong-Chuang Zhu, Zhuo-Ru Yang, Ai-Xi Hu, Gao Cao
Turkish Journal of Chemistry
Six novel 2,5-bis[4-(2-arylvinyl)phenyl]-1,3,4-oxadiazoles were synthesized by introducing 1,3,4-oxadiazole moiety into the stilbene skeleton. The synthesis route included the cyclization of p-toluic acid and hydrazine hydrate catalyzed by polyphosphoric acid (PPA), bromination of 1,3-dibromo-5,5-dimethylhydantoin (DBDMH), esterification, and the Wittig-Horner reaction. All the title compounds were characterized by ^1H-NMR, MS, and elemental analysis. UV-Vis absorption and fluorescence emission spectra in THF solution were investigated; the compounds may have potential for use in organic optical materials.
Synthesis And In Vitro Anti-Helicobacter Pylori Activity Of 2-(Substituted Benzylthio)-5-(5-Nitro-2- Furyl)-1, 3, 4-Thiadiazole Derivatives, Hossein Nasr Isfahani, Khalil Faghihi, Atena Izadkhah, Meisam Shabanian
Synthesis And In Vitro Anti-Helicobacter Pylori Activity Of 2-(Substituted Benzylthio)-5-(5-Nitro-2- Furyl)-1, 3, 4-Thiadiazole Derivatives, Hossein Nasr Isfahani, Khalil Faghihi, Atena Izadkhah, Meisam Shabanian
Turkish Journal of Chemistry
Starting from (5-nitrofuran-2-yl)methylene diacetate, a new series of 2-[(substituted benzyl)thio]-5-(5-nitro-2-furyl)-1,3,4-thiadiazoles (6a-n) were synthesized and the structures of the compounds were determined using spectroscopic methods including mass spectrometry, ^1H-nuclear magnetic resonance, infrared spectroscopy, and elemental analysis. The in vitro anti-Helicobacter pylori activity of the synthesized compounds was evaluated by the disk diffusion method against the clinical isolates of Helicobacter pylori. The results indicated that most of the synthesized compounds exhibited significant inhibitory activity against H. pylori with respect to standard drug metronidazole. Compound 6l, containing the 2-chloro-6-fluorobenzylthio moiety, was the most potent compound tested.
Synthesis And In Vitro Anti-Helicobacter Pylori Activity Of 2-(Substituted Benzylthio)-5-(5-Nitro-2- Furyl)-1, 3, 4-Thiadiazole Derivatives, Negar Mohammadhosseini, Ali Asadipor, Bahram Letafat, Mohsen Vosooghi, Farideh Siavoshi, Abbas Shafiee, Alireza Foroumadi
Synthesis And In Vitro Anti-Helicobacter Pylori Activity Of 2-(Substituted Benzylthio)-5-(5-Nitro-2- Furyl)-1, 3, 4-Thiadiazole Derivatives, Negar Mohammadhosseini, Ali Asadipor, Bahram Letafat, Mohsen Vosooghi, Farideh Siavoshi, Abbas Shafiee, Alireza Foroumadi
Turkish Journal of Chemistry
Starting from (5-nitrofuran-2-yl)methylene diacetate, a new series of 2-[(substituted benzyl)thio]-5-(5-nitro-2-furyl)-1,3,4-thiadiazoles (6a-n) were synthesized and the structures of the compounds were determined using spectroscopic methods including mass spectrometry, ^1H-nuclear magnetic resonance, infrared spectroscopy, and elemental analysis. The in vitro anti-Helicobacter pylori activity of the synthesized compounds was evaluated by the disk diffusion method against the clinical isolates of Helicobacter pylori. The results indicated that most of the synthesized compounds exhibited significant inhibitory activity against H. pylori with respect to standard drug metronidazole. Compound 6l, containing the 2-chloro-6-fluorobenzylthio moiety, was the most potent compound tested.