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Physical Sciences and Mathematics Commons

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Theses/Dissertations

2016

Pure sciences

Applied Statistics

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Full-Text Articles in Physical Sciences and Mathematics

Monte Carlo Methods In Bayesian Inference: Theory, Methods And Applications, Huarui Zhang Dec 2016

Monte Carlo Methods In Bayesian Inference: Theory, Methods And Applications, Huarui Zhang

Graduate Theses and Dissertations

Monte Carlo methods are becoming more and more popular in statistics due to the fast development of efficient computing technologies. One of the major beneficiaries of this advent is the field of Bayesian inference. The aim of this thesis is two-fold: (i) to explain the theory justifying the validity of the simulation-based schemes in a Bayesian setting (why they should work) and (ii) to apply them in several different types of data analysis that a statistician has to routinely encounter. In Chapter 1, I introduce key concepts in Bayesian statistics. Then we discuss Monte Carlo Simulation methods in detail. Our …


Risk Estimation Toward A Natural History Model For Low Grade Glioma Patients, Anh Thi Hoang Pham May 2016

Risk Estimation Toward A Natural History Model For Low Grade Glioma Patients, Anh Thi Hoang Pham

Graduate Theses and Dissertations

Glioma is a common type of primary brain tumor that represents 28% of all brain tumors and 80% of malignant tumors. According to a recent study by the Centers for Disease Control and Prevention (CDC), gliomas account for 53%, 35% and 29% of all brain tumors (68%, 74% and 81% of malignant brain tumors) among children (aged 0-14), teenagers (aged 15-19) and young adults, respectively. Gliomas are often diagnosed through radiological imaging and histopathology. There are two main groups of gliomas following World Health Organization’s classification: Low grade gliomas (LGG), or grade I and II gliomas; and high grade gliomas …


Spread Trading In Corn Futures Market, Ryan D. Napier May 2016

Spread Trading In Corn Futures Market, Ryan D. Napier

Graduate Theses and Dissertations

The non-linear relationship between old crop – new crop year spreads in corn futures market and stock-to-use (S-U) ratios published by the United States Department of Agriculture is analyzed. Using a non-linear logarithmic smooth transition regression (LSTR) model, we capture asymmetric market behaviors in high and low S-U regimes. Capturing this relationship and understanding the non-linear aspects of the relationship is of interest of grain merchandizers and speculators in the market. A spread trading strategy is simulated for the sample period, January 1985 through April 2015, to determine if the non-linear relationship is a profitable arbitrage opportunity in the market.


Statistical Modeling Of The Temporal Dynamics In A Large Scale-Citation Network, Luis Javier Ek Jr. May 2016

Statistical Modeling Of The Temporal Dynamics In A Large Scale-Citation Network, Luis Javier Ek Jr.

Graduate Theses and Dissertations

Citation Networks of papers are vast networks that grow over time. The manner or the form a citation network grows is not entirely a random process, but a preferential attachment relationship; highly cited papers are more likely to be cited by newly published papers. The result is a network whose degree distribution follows a power law. This growth of citation network of papers will be modeled with a negative binomial regression coupled with logistic growth and/or Cauchy distribution curve. Then a Barabasi-Albert model, based on the negative binomial models, and a combination of the Dirichlet distribution and multinomial will be …


Identification Of Biomarkers For The Overall Survival Of Ovarian Cancer Patients, Kristi Mai May 2016

Identification Of Biomarkers For The Overall Survival Of Ovarian Cancer Patients, Kristi Mai

Graduate Theses and Dissertations

Rapid advance in sequencing technology has led to genome-wide analysis of genetic and epigenetic features simultaneously, making it possible to understand the biological mechanisms underlying cancer initiation and progression. However, how to identify important prognostic features poses a great challenge for both statistical modeling and computing. In this thesis, a network-based approach is applied to the Cancer Genome Atlas (TCGA) ovarian cancer data to identify important genes related to the overall survival of ovarian cancer patients. In the first step, a stepwise correlation-based selector is used to reduce the dimensionality of TCGA data, by filtering out a large number of …