Physical Sciences and Mathematics Commons^™

Equalization Of Loudspeakers And Enclosed Sound Fields, Xi Chen

Theses and Dissertations

Equalization of loudspeakers and enclosed sound fields has been a topic of considerable interest for decades. Confusion has often arisen among audio professionals regarding the feasibility of simultaneously equalizing a loudspeaker and the enclosed field (i.e., the “room”) it excites. Because of frustrations encountered in such efforts, some have advocated abandoning simultaneous equalization altogether. This dissertation discusses the drawbacks of this approach as well as traditional in situ equalization methods. It demonstrates that many problems with traditional equalization stem from the use of measured acoustic pressure at a discrete point in a sound field as the system output. The dissertation …

Empirical Determination And Forecastability Of Foreign Exchange Rate Of India., Rituparna Kar Dr.

Doctoral Theses

The first chapter of this thesis begins with a brief review of the existing literature on foreign exchange rate models and their forecasting performance. Thereafter it presents the motivation as well as the main aspects of this study. The format of this chapter is as follows. A brief review of the relevant literature is presented in the first section. This review includes the important theoretical / structural as well as time series models of exchange rate. The motivation of the thesis is discussed in Section 1.2. Section 1.3 presents a brief account of the Indian economic reforms since 1993 with …

Predicting Flavonoid Ugt Regioselectivity With Graphical Residue Models And Machine Learning., Arthur Rhydon Jackson

Electronic Theses and Dissertations

Machine learning is applied to a challenging and biologically significant protein classification problem: the prediction of flavonoid UGT acceptor regioselectivity from primary protein sequence. Novel indices characterizing graphical models of protein residues are introduced. The indices are compared with existing amino acid indices and found to cluster residues appropriately. A variety of models employing the indices are then investigated by examining their performance when analyzed using nearest neighbor, support vector machine, and Bayesian neural network classifiers. Improvements over nearest neighbor classifications relying on standard alignment similarity scores are reported.

A Variation Of The Carleman Embedding Method For Second Order Systems., Charles Nunya Dzacka

Electronic Theses and Dissertations

The Carleman Embedding is a method that allows us to embed a finite dimensional system of nonlinear differential equations into a system of infinite dimensional linear differential equations. This technique works well when dealing with first-order nonlinear differential equations. However, for higher order nonlinear ordinary differential equations, it is difficult to use the Carleman Embedding method. This project will examine the Carleman Embedding and a variation of the method which is very convenient in applying to second order systems of nonlinear equations.

Vitis Seeds (Vitaceae) From The Late Neogene Gray Fossil Site, Northeastern Tennessee, Usa., Fade Gong

Electronic Theses and Dissertations

This study focuses on the morphometric and systematic studies of fossil vitaceous seeds recently recovered from the Gray Fossil Site (7-4.5 Ma, latest Miocene-earliest Pliocene) northeastern Tennessee. Morphologically, all fossil seeds correspond to the extant subgenus Vitis (genus Vitis) of the Vitaceae based on the smooth dorsal surface with a centrally positioned chalaza connected with a conspicuous chalaza-apex groove and short linear ventral infolds that are slightly diverged apically. A multivariate analysis based on 11 measured characters from 76 complete seeds identified three types of seeds, each representing a distinct morphotaxon. Based on comparison with modern and fossil vitaceous …

Determination Of The Activation Parameters Of Reaction Between [Fe(Cn6]-4 And K[Co(Hedta)No2]., Sammy Eni Eni

Electronic Theses and Dissertations

The kinetics of the oxidation of [Fe(CN)₆]^-4 by K[Co(HEDTA)NO₂] was studied in order to get the mechanism and the activation parameters of the reaction. Using a freshly-made Na₃PO₄ solution as the reaction medium with a pH of 6.00 the ionic strength was maintained at 0.10 M and the buffer molarity was 0.001 M.

The rate constant (k_obs) of the reaction between [Fe(CN)₆]^-4 and K[Co(HEDTA)NO₂] was determined at temperatures of 25.0°C, 27.5°C, 30.0°C, 35.0°, and 40.0°C. We explored this reaction by monitoring the evolution of ferricyanide, …

Modulation Of Restriction Enzyme Pvuii Activity By Metal Ion Cofactors, Charulata Bhaskaran Prasannan

Dissertations

Metal ions like Ca2+, Mn2+, Tb3+, Eu3+ etc., can bind at the active site and have varying effects on the enzymatic activity. In a crystal structure with DNA, two Ca2+ ions were bound to the active site of each PvuII monomer, and the metals share the ligands. Ca2+ ions promote DNA binding and not cleavage in many nucleases. We explored the role of Mg2+ and Ca2+ binding at the metal binding sites of PvuII to elucidate the role of each metal site. We monitored the cleavage kinetics of PvuII in presence of mixed metals. The cleavage kinetics data for Ca2+ …

Replacing Hydrogen Bonds With Coordinate Covalent Bonds In Coordination Networks, Colin Stewart Rodger

Dissertations

The overall theme of the dissertation is that metal ions such as silver(I) can replace H+ in hydrogen bonded organic frameworks. Because organic solids have been extensively studied, we can insert metal ions into the supramolecular assemblies, thus creating predictable coordination solids of varying dimensions. One example of an organic solid tested involves the organic compounds terephthalic and isophthalic acids. These dicarboxylic acids have previously been shown to self-assemble into tape-like structures via hydrogen bonding, with neighboring dicarboxylic acids located at angles of 180° and 120° respectively. By substituting the hydrogen bonds with coordination metal-ligand bonds similar assemblies are formed. …

Design And Synthesis Of Boronic Acid-Modified Nucleotides For Fluorescent Sensing And Cell Imaging, Xiaochuan Yang

Chemistry Dissertations

With the rapidly increasing interest in the field of glycomics, which is the comprehensive study of the roles carbohydrates play in a living system, urgent need for developing quick and highly selective carbohydrate sensors is growing. The boronic acid group, with its electron-deficient structure (6 valence electrons with an open shell), acts as a Lewis acid with high intrinsic affinity towards Lewis bases such as fluoride, cyanide and hydroxyl groups. Specifically, formation of a 5- or 6- membered ring between the boronic acid moiety and a1,2- or 1,3-diol in aqueous solution has been fully explored as a strategy of carbohydrate …

Carbon Coated Tellurium For Optical Data Storage, Jonathan D. Abbott

Theses and Dissertations

A highly durable optical disk has been developed for data archiving. This optical disk uses tellurium as the write layer and carbon as a dielectric and oxidation prevention layer. The sandwich style CTeC film was deposited on polycarbonate and silicon substrates by plasma sputtering. These films were then characterized with SEM, TEM, EELS, ellipsometry, ToF-SIMS, etc, and were tested for writability and longevity. Results show the films were uniform in physical structure, are stable, and able to form permanent pits. Data was written to a disk and successfully read back in a commercial DVD drive.

An Investigation Into Rewriting A Security Policy For Loreto College, Paul M. Mwai

Regis University Student Publications (comprehensive collection)

Computers as well as the networking environments in which they operate have evolved into highly sophisticated and complex systems. The intricacy of these systems and especially the relationship between them forms the greatest area of vulnerabilities for organizations. (Whitman and Mattord, 2004) Information needs to be transmitted to and from the organization, and thus may be vulnerable within certain stages along the communications line. If at any stage of the process, the information is compromised, it could have a negative impact on the entire organization. Protective measures such as disaster recover plans, encryption/ decryption, and information system security controls, can …

Realizing The Technical Advantages Of Star Transformation, Karen L. Darling

Regis University Student Publications (comprehensive collection)

Data warehousing and business intelligence go hand in hand, each gives the other purpose for development, maintenance and improvement. Both have evolved over a few decades and build upon initial development. Management initiatives further drive the need and complexity of business intelligence, while in turn expanding the end user community so that business change, results and strategy are affected at the business unit level. The literature, including a recent business intelligence user survey, demonstrates that query performance is the most significant issue encountered. Oracle's data warehouse 10g.2 is examined with improvements to query optimization via "best practice" through Star Transformation. …

A Review Of Offshore Wind Technology And The Development Of The Virginia Coastline And Outer Continental Shelf, Ryan D. Geary

Masters Theses, 2010-2019

Offshore wind power is an increasingly viable resource that is being considered by many coastal States in the U.S for development. This thesis provides a recommendation concerning the foundations that will be needed for the construction of offshore wind farms off the coast of Virginia. To accomplish this I reviewed current and prototype underwater foundation technologies in order to establish viable options for developers to use. I was also able to analyze a case study that conducted “an analysis and survey of the experiences and lessons learned by developers of offshore wind farms” in Europe. This case study focuses mainly …

A Simulation Model For Triclosan Concentrations In The North And Middle Rivers, Virginia, Preeyaporn Songkiatisak

Masters Theses, 2010-2019

Incidences of fish kills and intersex phenomena have occurred extensively in the Shenandoah River since 2004. Pharmaceuticals including triclosan have been detected at low concentrations in the Shenandoah River. Scientists hypothesize that triclosan, an antibacterial agent, may be one of the pharmaceuticals that is responsible for fish kills and intersex phenomena. Methyl triclosan (MTS) were found in fish tissues at a significantly higher concentration in the part of the Shenandoah River where fish kills are present compared to a non-impact river. Triclosan is widely used in personal care products, such as soaps, shampoos, and toothpastes and is rinsed down the …

Progress Toward The Total Synthesis Of Lyconadin A, Yu Zhang

Theses and Dissertations

Lyconadin A is a pentacyclic Lycopodium alkaloid isolated from the club moss Lycopodium complanatum with antitumor properties. We have developed a novel 7-exo/6-exo acyl radical cascade cyclization as a method of making the bicyclo[5.4.0]undecane ring system of lyconadin A. The model products are trans-fused ring systems, while a cis-fused ring system is needed in lyconadin A. We have discovered a method to convert the trans-fused model cascade cyclization product into the desired cis isomer. Based on Donohoe's pyridone synthesis, we developed a method for the construction of 5-alkyl and 3,5-dialkyl-6-carbomethoxy-2-pyridones, the former of which …

Analysis Of Electromagnetic And Seismic Geophysical Methods For Investigating Shallow Sub-Surface Hydrogeology, Eric M. Parks

Theses and Dissertations

An integrated electromagnetic (EM) and seismic geophysical study was performed to evaluate non-invasive approaches to estimate depth to shallow groundwater in arid environments with elevated soil salinity where the installation of piezometers would be impractical or prohibited. Both methods were tested in two study areas (semi-arid and arid respectively), one in Palmyra, Utah, USA near the shore of Utah Lake where groundwater is shallow and unconfined in relatively homogeneous lacustrine sediments. The other area is Carson Slough, Nevada, USA near Ash Meadows National Wildlife Refuge in Amargosa Valley. The area is underlain by valley fill, with generally variable shallow depths …

Large-Scale Distributed Coalition Formation, Daniel R. Karrels

Theses and Dissertations

The CyberCraft project is an effort to construct a large scale Distributed Multi-Agent System (DMAS) to provide autonomous Cyberspace defense and mission assurance for the DoD. It employs a small but flexible agent structure that is dynamically reconfigurable to accommodate new tasks and policies. This document describes research into developing protocols and algorithms to ensure continued mission execution in a system of one million or more agents, focusing on protocols for coalition formation and Command and Control. It begins by building large-scale routing algorithms for a Hierarchical Peer to Peer structured overlay network, called Resource-Clustered Chord (RC-Chord). RC-Chord introduces the …

Analysis Of Expedient Field Decontamination Methods For The Xmx/2l-Mil High-Volume Aerosol Sampler, Brandon C. Laroche

Theses and Dissertations

The XMX/2L-MIL is a high volume air sampler used by the Air Force Bioenvironmental Engineering community to collect biological aerosols. Without a verified decontamination technique, however, the XMX cannot be used effectively. The objective of this study was to evaluate several proposed methods for expedient field decontamination of the XMX. This study centered on the inactivation of Bacillus atrophaeus spores and vegetative Erwinia herbicola organisms from the XMX inner canister. The goals in this investigation were twofold: 1) to verify the antimicrobial efficacy of a 10% bleach solution and 2) to determine if wiping the components with a bleach-soaked paper …

Bisecting Document Clustering Using Model-Based Methods, Aaron Samuel Davis

Theses and Dissertations

We all have access to large collections of digital text documents, which are useful only if we can make sense of them all and distill important information from them. Good document clustering algorithms that organize such information automatically in meaningful ways can make a difference in how effective we are at using that information. In this paper we use model-based document clustering algorithms as a base for bisecting methods in order to identify increasingly cohesive clusters from larger, more diverse clusters. We specifically use the EM algorithm and Gibbs Sampling on a mixture of multinomials as the base clustering algorithms …

Midwave Infrared Imaging Fourier Transform Spectrometry Of Combustion Plumes, Kenneth C. Bradley

Theses and Dissertations

A midwave infrared (MWIR) imaging Fourier transform spectrometer (IFTS) was used to successfully capture and analyze hyperspectral imagery of combustion plumes. Jet engine exhaust data from a small turbojet engine burning diesel fuel at a flow rate of 300 cm³/min was collected at 1 cm⁻¹ resolution from a side-plume vantage point on a 200x64 pixel window at a range of 11.2 meters. Spectral features of water, CO, and CO² were present, and showed spatial variability within the plume structure. An array of thermocouple probes was positioned within the plume to aid in temperature analysis. A single-temperature …

Interactive Football Summarization, Brandon B. Moon

Theses and Dissertations

Football fans do not have the time to watch every game in its entirety and need an effective solution that summarizes them the story of the game. Human-generated summaries are often too short, requiring time and resources to create. We utilize the advantages of Interactive TV to create an automatic football summarization service that is cohesive, provides context, covers the necessary plays, and is concise. First, we construct a degree of interest function that ranks each play based on detailed, play-by-play game events as well as viewing statistics collected from an interactive viewing environment. This allows us to select the …

Multidimensional Methods: Applications In Drug-Enzyme Intrinsic Clearance Determination And Comprehensive Two-Dimensional Liquid Chromatography Peak Volume Determination, Dennis Thekkudan

Theses and Dissertations

The goal of the first project was to evaluate strategies for determining the in vitro intrinsic clearance (CLint) of dextrorphan (DR) as metabolized by the UGT2B7 enzyme to obtain dextrorphan glucuronide (DR-G). A direct injection liquid chromatography-mass spectrometry (LC-MS) method was used to monitor products using the pseudo-first-order (PFO) model. Standard enzymatic incubations were also quantified using LC-MS. These data were fit utilizing both PFO and Michaelis-Menten (MM) models to determine estimates of kinetic parameters. The CLint was determined to be 0.28 (± 0.08) µL/min/mg protein for a baculovirus insect cell-expressed UGT2B7 enzyme. This is the first confirmation that dextrorphan …

Noninvasive Estimation Of Pulmonary Artery Pressure Using Heart Sound Analysis, Aaron W. Dennis

Theses and Dissertations

Right-heart catheterization is the most accurate method for estimating pulmonary artery pressure (PAP). Because it is an invasive procedure it is expensive, exposes patients to the risk of infection, and is not suited for long-term monitoring situations. Medical researchers have shown that PAP influences the characteristics of heart sounds. This suggests that heart sound analysis is a potential noninvasive solution to the PAP estimation problem. This thesis describes the development of a prototype system, called PAPEr, which estimates PAP noninvasively using heart sound analysis. PAPEr uses patient data with machine learning algorithms to build models of how PAP affects heart …

An Adaptive Bayesian Approach To Dose-Response Modeling, Thomas J. Leininger

Theses and Dissertations

Clinical drug trials are costly and time-consuming. Bayesian methods alleviate the inefficiencies in the testing process while providing user-friendly probabilistic inference and predictions from the sampled posterior distributions, saving resources, time, and money. We propose a dynamic linear model to estimate the mean response at each dose level, borrowing strength across dose levels. Our model permits nonmonotonicity of the dose-response relationship, facilitating precise modeling of a wider array of dose-response relationships (including the possibility of toxicity). In addition, we incorporate an adaptive approach to the design of the clinical trial, which allows for interim decisions and assignment to doses based …

Analyzing Spatial Patterns In Reefscape Ecology Via Remote Sensing, Benthic Habitat Mapping, And Morphometrics, Shanna K. Dunn

HCNSO Student Theses and Dissertations

A growing number of scientists are investigating applications of landscape ecology principles to marine studies, yet few coral reef scientists have examined spatial patterns across entire reefscapes with a holistic ecosystem-based view. This study was an effort to better understand reefscape ecology by quantitatively assessing spatial structures and habitat arrangements using remote sensing and geographic information systems (GIS).

Quantifying recurring patterns in reef systems has implications for improving the efficiency of mapping efforts and lowering costs associated with collecting field data and acquiring satellite imagery. If a representative example of a reef is mapped with high accuracy, the data derived …

Nanoscopic Investigation Of Surface Morphology Of Neural Growth Cones And Indium Containing Group-Iii Nitrides, Göksel Durkaya

Physics and Astronomy Dissertations

This research focuses on the nanoscopic investigation of the three-dimensional surface morphology of the neural growth cones from the snail Helisoma trivolvis, and InN and InGaN semiconductor material systems using Atomic Force Microscopy (AFM). In the analysis of the growth cones, the results obtained from AFM experiments have been used to construct a 3D architecture model for filopodia. The filopodia from B5 and B19 neurons have exhibited different tapering mechanisms. The volumetric analysis has been used to estimate free Ca2+ concentration in the filopodium. The Phase Contrast Microscopy (PCM) images of the growth cones have been corrected to thickness provided …

Integrating Information Theory Measures And A Novel Rule-Set-Reduction Tech-Nique To Improve Fuzzy Decision Tree Induction Algorithms, Nael Mohammed Abu-Halaweh

Computer Science Dissertations

Machine learning approaches have been successfully applied to many classification and prediction problems. One of the most popular machine learning approaches is decision trees. A main advantage of decision trees is the clarity of the decision model they produce. The ID3 algorithm proposed by Quinlan forms the basis for many of the decision trees’ application. Trees produced by ID3 are sensitive to small perturbations in training data. To overcome this problem and to handle data uncertainties and spurious precision in data, fuzzy ID3 integrated fuzzy set theory and ideas from fuzzy logic with ID3. Several fuzzy decision trees algorithms and …

Analysis Of Gan/Alxga1?Xn Heterojunction Dual-Band Photodetectors Using Capacitance Profiling Techniques, Laura E. Byrum

Physics and Astronomy Theses

Capacitance-voltage-frequency measurements on n+-GaN/AlxGa1−xN UV/IR dual-band detectors are reported. The presence of shallow Si-donor, deep Si-donor, and C-donor/N-vacancy defect states were found to significantly alter the electrical characteristics of the detectors. The barrier Al fraction was found to change the position of the interface defect states relative to the Fermi level. The sample with Al fraction of 0.1 shows a distinct capacitance-step and hysteresis, which is attributed to C-donor/N-vacancy electron trap states located above the Fermi level (200 meV) at the heterointerface; whereas, the sample with Al fraction of 0.026 shows negative capacitance and dispersion, indicating C-donor/N-vacancy and deep Si-donor …

Open Heavy Flavor Measurement At Forward Angles For Cu+Cu Collisions At Center Of Mass Nn Collision Energy 200 Gev, Irakli Garishvili

Doctoral Dissertations

The main purpose of Relativistic Heavy Ion Collider (RHIC) program is to study the Quark-Gluon Plasma (QGP), a deconfined state of matter believed to be created in ultra-relativistic heavy ion collisions. Heavy quarks, expected to be produced during the earlier stages of heavy ion collisions, serve as an important probe of the QGP.‎

‎The following dissertation presents measurements of single muons resulting from the semileptonic decay of heavy flavor quarks in the rapidity range of $1.4 < \vert\eta\vert < 1.9$ for Cu+Cu nuclei collisions at $\sqrt{s_{NN}}=200$ GeV measured by the PHENIX experiment. Single muon spectra were measured for three different centrality classes (0 - 20 \% , 20 - 40 \%, 40 - 94 \%) within the $p_{T}$ range of 1.0 - 4.0 GeV/c.‎

‎To calculate single muon spectra, a full background estimate was statistically subtracted from inclusive spectra of muon candidate tracks reconstructed in the PHENIX muon …

Beta-Decay, Beta-Delayed Neutron Emission And Isomer Studies Around 78Ni, Mustafa Moiz Rajabali

Doctoral Dissertations

A study of nuclei with few nucleons outside the closed shell provides benchmarks for the nuclear shell model especially in this modern era of physics where exotic doubly magic nuclei can be tested. The subject of this thesis is to experimentally investigate the properties of nuclei near ⁷⁸Ni and to confront them with the predictions of modern large scale shell model calculations. In this regard, an experiment was performed at the National Superconducting Cyclotron Laboratory (NSCL) to measure excited states in ^71-73Ni populated via the beta-decay of ^71-73Co. Data collected from this experiment lead to partial level …