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Full-Text Articles in Physical Sciences and Mathematics
The Metabolic Change Of Lipid Species In Stam Mice With Hepatocellular Carcinoma, Devin J. Peart
The Metabolic Change Of Lipid Species In Stam Mice With Hepatocellular Carcinoma, Devin J. Peart
UNLV Theses, Dissertations, Professional Papers, and Capstones
Primary liver cancer hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide. In the US, primary liver cancer is the most rapidly increasing type of cancer due to increases in hepatitis B and C and the continued trend of greater and greater percentages of the population suffering from obesity, diabetes mellitus and metabolic syndrome. The prognosis for this disease is poor, with a 5-year survival rate of 26% as compared to only 2% when the cancer is metastatic. Unfortunately, current strategies for early detection of HCC, including routine CT imaging or alpha-fetoprotein biomarker, are suboptimal and tend …
Monte Carlo Simulation Of Thallium-Bromide Semiconductor Detector For Range Verification Of A Carbon Ion Radiotherapy Beam Through Prompt Gamma-Ray Detection, Peter Dimpfl
UNLV Theses, Dissertations, Professional Papers, and Capstones
Thallium-Bromide is a semiconductor material which is well suited for photon detection. Composed of high atomic number elements and a high mass density of 7.56 g/cm3, TlBr has superb photon stopping power. External beam radiation therapy is an ever-changing environment with technology rapidly improving. With proton therapy facilities becoming more widely available, and carbon ion facilities showcasing the benefits of carbon ion radiation therapy, there is an industry need toprovide accurate dosimetric treatment plans to verify patients are receiving proper care. Current clinical practices apply safety margins to clinical target volumes to safe treatment. Through research to improve detection techniques, …