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Full-Text Articles in Physical Sciences and Mathematics

Singular Superposition/Boundary Element Method For Reconstruction Of Multi-Dimensional Heat Flux Distributions With Application To Film Cooling Holes, Mahmood Silieti, Eduardo Divo, Alain J. Kassab Jan 2009

Singular Superposition/Boundary Element Method For Reconstruction Of Multi-Dimensional Heat Flux Distributions With Application To Film Cooling Holes, Mahmood Silieti, Eduardo Divo, Alain J. Kassab

Publications

A hybrid singularity superposition/boundary element-based inverse problem method for the reconstruction of multi-dimensional heat flux distributions is developed. Cauchy conditions are imposed at exposed surfaces that are readily reached for measurements while convective boundary conditions are unknown at surfaces that are not amenable to measurements such as the walls of the cooling holes. The purpose of the inverse analysis is to determine the heat flux distribution along cooling hole surfaces. This is accomplished in an iterative process by distributing a set of singularities (sinks) inside the physical boundaries of the cooling hole (usually along cooling hole centerline) with a given …


Models Of Phototransduction In Rod Photoreceptors, Harihar Khanal, Vasilios Alexiades Jan 2008

Models Of Phototransduction In Rod Photoreceptors, Harihar Khanal, Vasilios Alexiades

Publications

Phototransduction is the process by which photons of light generate an electrical response in retinal rod and cone photoreceptors, thereby initiating vision. We compare the electrical response in salamander rods from increasingly more (spacialy) detailed models of phototransduction: 0-dimensional (bulk), 1-dimensional (longitudinal), 2-dimensional (axisymmetric), and 3-dimensional (with incisures). We discuss issues of finding physical parameters for simulation and validation of models, and also present some computational experiments for rods with geometry of mouse and human photoreceptors.


Numerical Simulation Of Waves And Fronts In Inhomogeneous Solids, A. Berezovski, M. Berezovski, J. Engelbrecht, G. A. Maugin Jun 2007

Numerical Simulation Of Waves And Fronts In Inhomogeneous Solids, A. Berezovski, M. Berezovski, J. Engelbrecht, G. A. Maugin

Publications

Dynamic response of inhomogeneous materials exhibits new effects, which often do not exist in homogeneous media. It is quite natural that most of studies of wave and front propagation in inhomogeneous materials are associated with numerical simulations. To develop a numerical algorithm and to perform the numerical simulations of moving fronts we need to formulate a kinetic law of progress relating the driving force and the velocity of the discontinuity. The velocity of discontinuity is determined by means of the non-equilibrium jump relations at the front. The obtained numerical method generalizes the wave-propagation algorithm to the case of moving discontinuities …


Multiphoton Response Of Retinal Rod Photoreceptors, Vasilios Alexiades, Harihar Khanal Jan 2007

Multiphoton Response Of Retinal Rod Photoreceptors, Vasilios Alexiades, Harihar Khanal

Publications

Phototransduction is the process by which light is converted into an electrical response in retinal photoreceptors. Rod photoreceptors contain a stack of (about 1000) disc membranes packed with photopigment rhodopsin molecules, which absorb the photons. We present computational experiments which show the profound effect on the response of the distances (how many discs apart) photons happen to be absorbed at. This photon-distribution effect alone can account for much of the observed variability in response.


Numerical Simulation Of Nonlinear Elastic Wave Propagation In Piecewise Homogeneous Media, Arkadi Berezovski, Mihhail Berezovski, Juri Engelbrecht Jan 2006

Numerical Simulation Of Nonlinear Elastic Wave Propagation In Piecewise Homogeneous Media, Arkadi Berezovski, Mihhail Berezovski, Juri Engelbrecht

Publications

Systematic experimental work [S. Zhuang, G. Ravichandran, D. Grady, J. Mech. Phys. Solids 51 (2003) 245–265] on laminated composites subjected to high velocity impact loading exhibits the dispersed wave field and the oscillatory behavior of waves with respect to a mean value. Such a behavior is absent in homogeneous solids. An approximate solution to the plate impact in layered heterogeneous solids has been developed in [X. Chen, N. Chandra, A.M. Rajendran, Int. J. Solids Struct. 41 (2004) 4635–4659]. The influence of the particle velocity on many process characteristics was demonstrated. Based on earlier results [A. Berezovski, J. Engelbrecht, G.A. Maugin, …


On Doubly Periodic Solutions Of Quasilinear Hyperbolic Equations Of The Fourth Order, T. Kiguradze, T. Smith Jan 2006

On Doubly Periodic Solutions Of Quasilinear Hyperbolic Equations Of The Fourth Order, T. Kiguradze, T. Smith

Publications

The problem on doubly periodic solutions is considered for a class of quasilinear hyperbolic equations. Effective sufficient conditions of solvability and unique solvability of this problem are established.


Transient Non-Linear Heat Conduction Solution By A Dual Reciprocity Boundary Element Method With An Effective Posteriori Error Estimator, Eduardo Divo, Alain J. Kassab Jan 2005

Transient Non-Linear Heat Conduction Solution By A Dual Reciprocity Boundary Element Method With An Effective Posteriori Error Estimator, Eduardo Divo, Alain J. Kassab

Publications

A Dual Reciprocity Boundary Element Method is formulated to solve non-linear heat conduction problems. The approach is based on using the Kirchhoff transform along with lagging of the effective non-linear thermal diffusivity. A posteriori error estimate is used to provide effective estimates of the temporal and spatial error. A numerical example is used to demonstrate the approach.


Response Of Dark-Adapted Retinal Rod Photoreceptors, H. Khanal, V. Alexiades, E. Dibenedetto Jan 2004

Response Of Dark-Adapted Retinal Rod Photoreceptors, H. Khanal, V. Alexiades, E. Dibenedetto

Publications

The process of phototransduction, whereby light is converted into an electrical response, in rod and cone photoreceptors in the retina, involves as a key setp, the diffusion of the cytoplasmic, signaling molecules cGMP (cyclic guanosime monophosphate) and Ca2+ diffuse in the cytoplasm (the fluid surrounding the discs). the complex geometry of the rod creates computational difficulties. We present spatio-temporal compuational models for interacctions and diffusion of cGMP and Ca2+ in the cytoplasm of vertebrate rod photoreceptors, as well as numerical simulations fo the response to light of dark-adapted Salamander rods.


Computational Models For Diffusion Of Second Messengers In Visual Transduction, Harihar Khanal Aug 2003

Computational Models For Diffusion Of Second Messengers In Visual Transduction, Harihar Khanal

Publications

The process of phototransduction, whereby light is converted into an electrical response in retinal rod and cone photoreceptors, involves, as a crucial step, the diffusion of cytoplasmic signaling molecules, termed second messengers. A barrier to mathematical and computational modeling is the complex geometry of the rod outer segment which contains about 1000 thin discs. Most current investigations on the subject assume a well-stirred bulk aqueous environment thereby avoiding such geometrical complexity. We present theoretical and computational spatio-temporal models for phototransduction in vertebrate rod photoreceptors, which are pointwise in nature and thus take into account the complex geometry of the …