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Full-Text Articles in Physical Sciences and Mathematics
Modeling And Control Of Nanoparticle Bloodstream Concentration For Cancer Therapies, Scarlett S. Bracey
Modeling And Control Of Nanoparticle Bloodstream Concentration For Cancer Therapies, Scarlett S. Bracey
Doctoral Dissertations
Currently, the most commonly used treatments for cancerous tumors (chemotherapy, radiation, etc.) have almost no method of monitoring the administration of the treatment for adverse effects in real time. Without any real time feedback or control, treatment becomes a "guess and check" method with no way of predicting the effects of the drugs based on the actual bioavailability to the patient's body. One particular drug may be effective for one patient, yet provide no benefit to another. Doctors and scientists do not routinely attempt to quantifiably explain this discrepancy. In this work, mathematical modeling and analysis techniques are joined together …
A Mathematical Model And Numerical Method For Thermoelectric Dna Sequencing, Liwei Shi
A Mathematical Model And Numerical Method For Thermoelectric Dna Sequencing, Liwei Shi
Doctoral Dissertations
DNA sequencing is the process of determining the precise order of nucleotide bases, adenine, guanine, cytosine, and thymine within a DNA molecule. It includes any method or technology that is used to determine the order of the four bases in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Thermoelectric DNA sequencing is a novel method to sequence DNA by measuring the heat that is released when DNA polymerase inserts a deoxyribonucleoside triphosphate into a growing DNA strand. The thermoelectric device for this project is composed of four parts: …
Generalized Finite-Difference Time-Domain Schemes For Solving Nonlinear Schrödinger Equations, Frederick Ira Moxley Iii
Generalized Finite-Difference Time-Domain Schemes For Solving Nonlinear Schrödinger Equations, Frederick Ira Moxley Iii
Doctoral Dissertations
The nonlinear Schrödinger equation (NLSE) is one of the most widely applicable equations in physical science, and characterizes nonlinear dispersive waves, optics, water waves, and the dynamics of molecules. The NLSE satisfies many mathematical conservation laws. Moreover, due to the nonlinearity, the NLSE often requires a numerical solution, which also satisfies the conservation laws. Some of the more popular numerical methods for solving the NLSE include the finite difference, finite element, and spectral methods such as the pseudospectral, split-step with Fourier transform, and integrating factor coupled with a Fourier transform. With regard to the finite difference and finite element methods, …