Physical Sciences and Mathematics Commons^™

Characterization Of A Biosynthetic Pathway Yielding Anticancer Natural Products From A Marine Bacterium, Elle D. James

UNF Graduate Theses and Dissertations

Natural products are bioactive secondary metabolites produced by living organisms and are prevalently utilized as pharmaceutical drugs. Marine adapted organisms are a promising source of new natural products possessing unique chemical structures and biological activities. By studying the biosynthetic pathways employed by living organisms to produce natural products, insights into new strategies to generate molecules to combat disease and overcome drug resistance may be gained. This thesis study aimed to uncover the biosynthetic pathway employed by a marine actinomycete, Nocardiopsis sp. CMB-M0232, to catalyze the assembly of the nocardioazines. These molecules are a group of 2,5-diketopiperazine natural products that feature …

Effects Of Prescribed Fire On Upland Plant Biodiversity And Abundance In Northeast Florida, Peter D. Maholland

UNF Graduate Theses and Dissertations

Terrestrial ecosystems in the southeastern United States have evolved with fire as a common disturbance and as a result many natural communities require the presence of fire to persist over time. Human development precludes natural fires from occurring within these communities; however, prescribed fire is considered to be a critical tool in the effort to restore fire-dependent ecosystems after decades of fire exclusion. Direct effects of fire on individual floral and faunal species as well as benefits to biodiversity at the landscape (gamma diversity) level have largely been supported in previous research. However, information on the effects of natural and …

Time Series Similarity Search In Distributed Key-Value Data Stores Using R-Trees, Aleksey Charapko

UNF Graduate Theses and Dissertations

Time series data are sequences of data points collected at certain time intervals. The advance in mobile and sensor technologies has led to rapid growth in the available amount of time series data. The ability to search large time series data sets can be extremely useful in many applications. In healthcare, a system monitoring vital signals can perform a search against the past data and identify possible health threatening conditions. In engineering, a system can analyze performances of complicated equipment and identify possible failure situations or needs of maintenance based on historical data.

Existing search methods for time series data …

The Simulation & Evaluation Of Surge Hazard Using A Response Surface Method In The New York Bight, Michael H. Bredesen

UNF Graduate Theses and Dissertations

Atmospheric features, such as tropical cyclones, act as a driving mechanism for many of the major hazards affecting coastal areas around the world. Accurate and efficient quantification of tropical cyclone surge hazard is essential to the development of resilient coastal communities, particularly given continued sea level trend concerns. Recent major tropical cyclones that have impacted the northeastern portion of the United States have resulted in devastating flooding in New York City, the most densely populated city in the US. As a part of national effort to re-evaluate coastal inundation hazards, the Federal Emergency Management Agency used the Joint Probability Method …

Mobile Cloud Computing: Offloading Mobile Processing To The Cloud, Jesus Zambrano

UNF Graduate Theses and Dissertations

The current proliferation of mobile systems, such as smart phones, PDA and tablets, has led to their adoption as the primary computing platforms for many users. This trend suggests that designers will continue to aim towards the convergence of functionality on a single mobile device. However, this convergence penalizes the mobile system in computational resources such as processor speed, memory consumption, disk capacity, as well as in weight, size, ergonomics and the user’s most important component, battery life. Therefore, this current trend aims towards the efficient and effective use of its hardware and software components. Hence, energy consumption and response …

Integrating Security Into The Undergraduate Software Engineering Curriculum, Robert Evans

UNF Graduate Theses and Dissertations

This research included a thorough examination of the existing software assurance or what is commonly called software security knowledge, methodologies and what information security technologies is currently being recommended by the information technology community. Finally it is demonstrated how this security knowledge could be incorporated into the curriculum for undergraduate software engineering.

A Comparison Of Cloud Computing Database Security Algorithms, Joseph A. Hoeppner

UNF Graduate Theses and Dissertations

The cloud database is a relatively new type of distributed database that allows companies and individuals to purchase computing time and memory from a vendor. This allows a user to only pay for the resources they use, which saves them both time and money. While the cloud in general can solve problems that have previously been too costly or time-intensive, it also opens the door to new security problems because of its distributed nature. Several approaches have been proposed to increase the security of cloud databases, though each seems to fall short in one area or another.

This thesis presents …

Comparing Group Means When Nonresponse Rates Differ, Gabriela M. Stegmann

UNF Graduate Theses and Dissertations

Missing data bias results if adjustments are not made accordingly. This thesis addresses this issue by exploring a scenario where data is missing at random depending on a covariate x. Four methods for comparing groups while adjusting for missingness are explored by conducting simulations: independent samples t-test with predicted mean stratification, independent samples t-test with response propensity stratification, independent samples t-test with response propensity weighting, and an analysis of covariance. Results show that independent samples t-test with response propensity weighting and analysis of covariance can appropriately adjust for bias. ANCOVA is the stronger method when …

Sorting By Block Moves, Jici Huang

UNF Graduate Theses and Dissertations

The research in this thesis is focused on the problem of Block Sorting, which has applications in Computational Biology and in Optical Character Recognition (OCR). A block in a permutation is a maximal sequence of consecutive elements that are also consecutive in the identity permutation. BLOCK SORTING is the process of transforming an arbitrary permutation to the identity permutation through a sequence of block moves. Given an arbitrary permutation π and an integer m, the Block Sorting Problem, or the problem of deciding whether the transformation can be accomplished in at most m block moves has been shown to be …