Physical Sciences and Mathematics Commons^™

The Staying Power Of Asbestos Hazards: A Critical Environmental Justice Case Analysis, Emily Qian

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Methods For Increasing The Electron Richness Of Iron Tricarbonyl Diimine Complexes, Francesca Lombardi, Joseph Maher, Sean Peloquin

Chemistry & Biochemistry Student Scholarship

Francesca Lombardi ’24, Major: Chemistry

Joseph Maher ’25, Major: Chemistry

Sean Peloquin ’26, Major: Biochemistry

Faculty Mentor: Dr. Maria Carroll, Chemistry and Biochemistry

The goal of our research is to synthesize new iron complexes that can reduce carbon dioxide. Increasing the electron richness of iron tricarbonyl diimine complexes, which have been synthesized previously in the Carroll research group, will increase the likelihood of a reaction with carbon dioxide occurring. We have taken two approaches to changing the electron density in the complexes. First, we reacted the complex Fe((CF3)2ArDABMe)(CO)¬3 with the reducing agent potassium on graphite, in order to reduce either …

Kinetic Analysis Of Glu115ala Cytosolic Human Malate Dehydrogenase Mutation Shows A Change In Activity On Non-Native Substrate Phenylpyruvate, Kailey Paar

Chemistry & Biochemistry Student Scholarship

The cytosolic human enzyme, malate dehydrogenase (MDH1), is believed to have a significant effect on the proliferation of cancerous cells. This enzyme oxidizes NADH to NAD+ as it converts oxaloacetate (OAA) to malate. This oxidation of NADH provides the needed NAD+ to cancer cells, which require NAD+ as they upregulate glycolysis in aerobic conditions. Targeting MDH1 can reveal new therapeutic treatments for cancer by preventing the conversion of OAA to malate and depleting NAD+ stores in cancer cells, which can be done by mutating residues in the enzyme and assessing the change in activity. Here we show the replacement of …

An Exploratory Study Of How Postoperative Bariatric Surgery Patients Use Online Communities For Support, Breisha George

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Exploring Indicator Displacement Assays For Phosphate Detection In Seawater, Francis Radics

Chemistry & Biochemistry Student Scholarship

Francis Radics ’22
Major: Biochemistry
Faculty Mentor: Dr. John Breen, Chemistry and Biochemistry

Indicator displacement assays are based on the optical signal modulation of a noncovalently bound indicator upon dissociation by an analyte species. Our work has focused on exploring the lower detection limits for luminescent displacement assays for inorganic phosphate in seawater using complex ions containing two di(2-picolyl)amine ligands (also called DPA or bis(2-pyridylmethyl)amine), each coordinating a zinc cation. Following the work of B.D. Smith and coworkers, we have prepared three ligands by covalently attaching two DPA moieties, 2,6-bis(chloromethyl) benzene, and 2,6-bis(chloromethyl)-4-methylphenol, and 1,2-phenylenedimethylamine, for assays with 6,7-dihydroxy-4-methanesulfonic acid …

Topological Data Analysis And Ant Interaction Networks, Adam Banatwala, Esther Rønn

Mathematics & Computer Science Student Scholarship

Adam Banatwala ’22, Majors: Mathematics and Finance
Esther Rønn ’23, Majors: Physics and Mathematics
Faculty Mentor: Dr. Laura Murray, Mathematics and Computer Science

Our research group used topological data analysis (TDA) to quantify the movement and behavior of ants in a colony.

We extracted higher dimensional networks from point cloud data collected from Dr. James Waters’ lab. Varying the proximity parameter in this construction gives a sequence of networks. We analyzed the enduring topological features of these networks, and how these features evolve over time as the ants move in the colony. Both the experimental and null model simulation data …

Promoting Sustainability At Providence College, Victoria Hanlon, Ava Biafore

Health Policy & Management Student Scholarship

Victoria Hanlon ’23, Major: Health Policy and Management

Ava Biafore ’23, Majors: Management and Health Policy and Management

Faculty Mentors: Dr. Tuba Agartan, Health Policy and Management and Jill Parrett, Environmental Health and Safety

We are both Health Policy and Management majors conducting an independent study with Dr. Agartan with the goal of improving sustainability practices at Providence College. We are working cross functionally with Jill Parret of the Environmental Safety Department and the Student Congress Sustainability Committee to encourage the student body to increase sustainability awareness. These measures include creating a sustainability dashboard on the Providence College website, Canva …

Classifications Of Transformations Of Km#Tn And Pm#Tn Via Symmetry Groups, Adam Banatwala, Jensen Barry, Mackenzie Maude

Mathematics & Computer Science Student Scholarship

Adam Banatwala ’22, Majors: Mathematics and Finance
Jensen Barry ’22, Majors: Biology and Mathematics
Mackenzie Maude ’22, Majors: Mathematics and Art History
Faculty Mentor: Dr. C. Joanna Su, Mathematics and Computer Science

One of the main topics in topology is the classification and comparison of shapes and surfaces. Since Spring 2020, our research group has been using symmetry groups to classify the 1- and 2-dimensional orientable and non-orientable closed surfaces.

First, the group worked on the symmetry groups of the 1- and 2-dimensional orientable closed surfaces; namely, the classification on V?? 1 (the one-point adjoint of n circles) …

The Effect Of Crude Oil Prices On Personal Consumption Expenditure, Eileen Cooney

Economics Student Scholarship

Eileen Cooney ’23
Majors: Quantitative Economics and Political Science
Minor: Finance
Faculty Mentor: Dr. Fang Dong, Economics

The author used the time series models to analyze how growth of personal consumption expenditure is influenced by financial and economic determinants. Results show that both oil price and consumer sentiment play important roles in influencing consumption growth.

Metal Complexes Of Redox Active Ligands, Alexandra Chaparro, Parker Keller

Chemistry & Biochemistry Student Scholarship

Alexandra Chaparro ’22, Major: Biochemistry

Parker Keller ’24, Major: Chemistry

Mentor: Dr. Maria Carroll, Chemistry and Biochemistry

Our research focuses on synthesizing and studying the properties of metal complexes that contain redox active ligands. Ligands are molecules or ions that can bind to a metal ion, and this particular class of ligands is interesting because they can either accept or lose electrons. We synthesized zinc complexes, in order to measure the reduction potentials of the ligands, which provide information about the ease with which they accept electrons. We then synthesized iron complexes and determined their structures. These complexes are potentially …

Lines On A Smooth Projective Surface, Jordan Demoura

Mathematics & Computer Science Student Scholarship

Jordan DeMoura ’22
Major: Mathematics
Faculty Mentor: Dr. Su-Jeong Kang, Math

This research is to investigate lines on a smooth projective surface. A quadric surface contains two families of planes that provide a ruling of the surface. A cubic surface contains twenty-seven lines, and we provide a complete description of these lines for a Fermat cubic surface. Furthermore, under the Plucker embedding, we show that each family of the lines on a quadric surface corresponds to plane conic curves lying on complementary planes in the projective space of dimension five.

A Damaged Reputation: Nuclear Depictions In Entertainment Media, Alexander Cannon

Chemistry & Biochemistry Student Scholarship

This paper, originally written for Dr. Adamus Liotta in an honors chemistry class, explores the possibility of a significant influence over public common sense found in the depictions of entertainment media. Through careful analysis and interpretation of Godzilla, The Simpsons, Fallout, and Call of Duty, this paper finds a synergy throughout this diverse range of audience, medium and historical origin, which culminates in an effect much greater than the sum of its parts. This effect frames nuclear science, of any kind, in a hyperbolically catastrophic and horrific light, reinforcing an excessively cautious, pessimistic public perspective on nuclear technology …

The Impact Of Decriminalizing Marijuana In Rhode Island On The Number Of Narcotic Related Arrests And Quantities Seized, Abigail Kojoian

Mathematics & Computer Science Student Scholarship

Major: Mathematics
Minor: Classics
Faculty Mentor: Dr. Asta Shomberg, Mathematics

Self-Supervised Learning For Single-Molecule Localization Microscopy, Clare Minnerath

Mathematics & Computer Science Student Scholarship

Major: Mathematics and Computer Science

Faculty Mentor: Dr. Lynette Boos, Mathematics

We evaluate the ability of self-supervised deep learning for Poisson denoising of Single-Molecule Localization Microscopy (SMLM) in addition to the impact denoising can have on the ability to locate molecules within the Single-Molecule Localization Microscopy images. SMLM images are predominantly corrupted with Poisson noise. There is a need for a superior technique to provide accurate SMLM images in order for scientists to gain a better understanding of the functions of live cells at the nanoscale. By denoising SMLM images prior to the images undergoing the current state- of-the-art super-resolution …

Research In Sabermetrics: The Cape Cod Baseball League, Thomas Zinzarella

Mathematics & Computer Science Student Scholarship

Major: Sports Media

Faculty Mentor: Fr. Humbert Kilanowski O.P, Mathematics and Computer Science

We analyzed data from the Cape Cod Baseball League, a prestigious summer baseball league, where we looked at sabermetric statistics such as WAR (Wins above replacement). Stats like these can help evaluate a player and project whether they are a future MLB player or not. Especially on the Cape, where 1 in 7 current Major League Baseball players have played in the league.

Simplexity Of The N-Cube, Peter Graziano

Mathematics & Computer Science Student Scholarship

Major: Mathematics and Classics

Faculty Mentor: Dr. Su-Jeong Kang, Mathematics

The process of dividing shapes into triangles is called triangulation, and it is possible to abstract the idea of a triangle to higher dimensions, where it will be called a simplex in n-dimensions, or an n-simplex. I studied this process of generalized triangulation, or decomposition, in order to find an optimal decomposition of a 5-cube to help improve the bounds on the general case of an n-cube.

Application Of Black-Scholes-Merton Model In Option Pricing And Intangibles Assets, Giang Nguyen-Hoang

Mathematics & Computer Science Student Scholarship

Major: Finance and Mathematics

Faculty Mentor: Dr. Joseph Shomberg, Mathematics

The Black-Scholes model was developed by Fisher Black and Myron Scholes in the 1970s to price stock options. Since then the model has been suited to price so-called intangible assets such as trademarks and patents. In this paper, we investigate the related Black-Scholes-Merton model and the relevant characteristics of patents in order to associate patents as real options. After describing patents as options, we apply the Black-Scholes-Merton model to the valuation of the intangible assets. Special attention is given to modeling volatility and the cost of delay in order to …

Towards The Development Of Low-Cost And Easily-Deployable Sensing Platforms For Phosphate, Maureen Pontarelli, Thomas Koch

Chemistry & Biochemistry Student Scholarship

Maureen Pontarelli ’20
Major: Chemistry

Thomas Koch '20
Major: Biochemistry

Faculty Mentor: Dr. John Breen, Chemistry and Biochemistry

Exploration Of K2 Mycobacteriophages With Bred​, Colby Agostino, Olivia Schmitt

Chemistry & Biochemistry Student Scholarship

Colby Agostino ’22
Major: Biochemistry and Computer Science

Olivia Schmitt ’22
Major: Biochemistry

Faculty Mentor: Dr. Kathleen A. Cornely, Chemistry and Biochemistry

ZoeJ and Marcoliusprime are mycobacteriophage capable of infecting tuberculosis causing bacteria via the lytic and lysogenic cycles. The lytic cycle is the form of viral replication that results in cell death. Lysogeny involves phage DNA being integrated with the DNA of the host cell and preserved through binary fission. However, the bacteria causing tuberculosis do not die in the lysogenic phase. This research project will involve creating mutants of ZoeJ and Marcoliusprime that will not contain the genes …

Mycobacteriophage Morphology As A Diagnostic For Cluster Assignment, Ethan Dionne

Chemistry & Biochemistry Student Scholarship

Major: Biochemistry

Faculty Mentor: Dr. Kathleen A. Cornely, Chemistry and Biochemistry

Phages are viral bodies that infect bacterial hosts, and have shown promising applications as alternatives to antibiotics for the treatment of bacterial infections. This project examines the morphology of siphoviridae mycobacteriophage, which have long, flexible, non-contractile tails as well as the characteristic head, called a capsid. Using electron microscopy photos of sequenced phages, tail length and capsid diameter were measured and compared to further characterize morphological relationships between genetically distinct phages. The data presented has the potential to work as a diagnostic tool to classify unsequenced phages to genetically …

Using Neural Networks To Classify Pdes, Julia Balukonis, Sabrina Fuller, Haley Rosso

Mathematics & Computer Science Student Scholarship

Major: Mathematics
Minor: Computer Science and Film

Faculty Mentor: Dr. Lynette Boos, Mathematics and Computer Science

We designed two neural networks that can learn how to classify three different types of partial differential equations (PDEs). Our data consists of numerical solutions to three categories of PDEs: Burger’s, Diffusion, and Transport equations. Using TensorFlow and the Keras library, we performed two tasks – the first a binary classification of Burger’s and Diffusion equation data, and the second a multi-label classification incorporating the Transport Equations as well. Our binary classification network requires vector labels to perform efficiently. Furthermore, our tertiary classification network …

Lab Without A Lab: Prospects For An Iolab Kit To Provide Hands-On Introductory Physics Laboratory Learning Experiences Outside The Traditional Setting, Seth T. Ashman

Engineering & Physics Faculty Publications

No abstract provided.

Surface Mutation Thr34his Facilitates Purification Of Haemophilus Influenza Carbonic Anhydrase Via Metal Affinity Chromatography, Caroline Foley, Dr. Kathleen Cornely

Chemistry & Biochemistry Student Scholarship

In order to pursue Haemophilus influenza carbonic anhydrase (HICA) as a potential drug target, easy and efficient purification methods must be developed. While immobilized metal affinity chromatography (IMAC) may be used, complications with polyhistidine tags is a concern. Inspired by the endogenous metal affinity of Escherichia coli β-carbonic anhydrase (ECCA), we suggest that the generation of histidine clusters on HICA’s surface will facilitate its purification by metal affinity chromatography without the potential interference of His-tags. Here we investigate the Thr34His mutation as a method to generate metal affinity in HICA. Since Thr34His is located only 5.3 Å away from His32, …

Vibrational State Resolved Lifetimes Of The Na2 21Σ+U Double Well State, Seth T. Ashman, Lutz Huwel, Roy Anunciado, Nadeepa Jayasundara

Engineering & Physics Faculty Publications

Lifetimes of individual Na2 ro-vibrational levels of the 21Σ + u double well-state have been measured using a delayed photoionization technique. Ground state Na2 produced in a molecular beam is excited resonantly by the doubled output of a pulsed dye laser in the range 333 – 357 nm and then ionized by a 532 nm photon from a time-delayed Nd:YAG laser. By appropriate excitation laser tuning and systematic variation of the probe laser delay, ro-vibrational level resolved lifetimes are obtained for v=25- 49. The double well state lifetime values are found to decrease from about 50 ns at v=25 to …

E56h + E59h Mutation Affects Binding Of The Recombinant Haemphilus Influenza Carbonic Anhydrase To A Ni-Nta Column, Eric D. Lebel, Kathleen Cornely

Chemistry & Biochemistry Student Scholarship

The Haemophilus influenzae carbonic anhy- drase (HICA) is important in converting carbon dioxide to bicarbonate in bacteria. Endogenous cellular proteins, like Escherichia coli carbonic anhydrase (ECCA), have been observed to bind to a Ni-NTA column, which can be used as a means of protein purification. The possibility ex- ists that proteins that do not normally bind to Ni-NTA, like HICA, can be engineered using site directed mutagenesis to introduce histidine resi- dues that would give the protein the capability to bind, allowing for a one-step purification method. Site-directed mutagenesis was used to introduce the double mutation of E56H + E59H …

Mutation Of Surface Histidines In Haemophilus Influenzae Carbonic Anhydrase To Enable Purification By Metal Affinity Chromatography, Shelby E. Scola, Kathleen Cornely

Chemistry & Biochemistry Student Scholarship

No abstract provided.

Comparison Of Absorption, Fluorescence, And Polarization Spectroscopy Of Atomic Rubidium, Seth T. Ashman, Cayla Stifler, Joaquin Romero

Engineering & Physics Faculty Publications

An ongoing spectroscopic investigation of atomic rubidium utilizes a two-photon, single-laser excitation process. Transitions accessible with our tunable laser include 5P1/2 (F ′ ) ← 5S1/2 (F) and 5P3/2 (F ′ ) ← 5S1/2 (F). The laser is split into a pump and probe beam to allow for Doppler-free measurements of transitions between hyperfine levels. The pump and probe beams are overlapped in a counter-propagating geometry and the laser frequency scans over a transition. Absorption, fluorescence and polarization spectroscopy techniques are applied to this basic experimental setup. The temperature of the vapor cell and the power of the pump and …

Transubstantiation And Quantum Physics: The Parallels Of Mystery In Religion And Science, Zachary Sexton

Spring 2013, Science and Religion

As the study of physics has progressed into the abstract realm of quanta, some have argued that the notion of transubstantiation is an unreasonable understanding of the Eucharist. However, when confronted with the uncertainty that modern physics presents, sharp parallels between this uncertainty and the metaphysical mysteries of transubstantiation. If it is reasonable to accept uncertainty in quantum physics, then it should be reasonable to accept the mysteries within the metaphysical world.

Heisenberg’S Uncertainty Principle, Matthew Santos

Spring 2013, Kuhn's Philosophy of Science

In 1926 Werner Heisenberg’s Uncertainty Principle set the field of quantum mechanics on a trajectory riddled with indeterminacy, a trajectory which stood in stark contrast with the classical Newtonian world causality and origin. In doing so, Heisenberg effectively created a new standard by which physicists conducted their science, broadened the scope of that science, and altered the very worldview of those physicists. Such paradigmatic upheaval fits the philosophical model of scientific progress posited by Thomas Kuhn. However, in the ever-changing and still-evolving world of quantum mechanics, Heisenberg’s revolutionary work uniquely strays from Kuhn’s model in its further implications.

Diffusion Of Mobile Payment Systems Among Microentrepreneurs In Kenya And Tanzania, Dionne Nickerson

Annual Celebration of Student Scholarship and Creativity

The rapid rise of Kenya's mobile payment system, M-PESA , has grasped the attention of policy makers and private enterprise alike. In just six years M-PESA has transformed how money flows throughout Kenya, and similar systems are gaining traction elsewhere in Africa. This project examines the impact of mobile payment system adoption on the economic advancement of Kenyan and Tanzanian microentrepreneurs. This work will further the understanding of mobile payment systems’ contribution to the economic growth of microenterprises, which may have implications for poverty reduction in these two nations.