Physical Sciences and Mathematics Commons^™

Metallopharmaceuticals As Photoactivatable Anticancer Drugs, Samar Moqadasi, Christine O'Connor, Denis O'Shea, Michael Devereux

Conference Papers

Target-based research (treating infected site only), directed towards the design and mechanism of action of metal-based anticancer complexes is expanding rapidly due to the selectivity and activity of such novel therapeutics. The photo activation of Ruthenium (II) complexes as therapeutic drugs has recently escalated as the complexes are suitable for photoactivation due to their well published photochemical and photophysical properties which in turn is the basis of photodynamic approaches to therapy.1-5 The aim of this study is to synthesise a series of metallo-complexes of which will be tested on tumour and non-tumour cell lines in the Radiation & Environmental Science …