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Novel Synthetic Transformations Targeting Δ-Valerolactone And Isocoumarin, Joshua Paul Van Houten
Novel Synthetic Transformations Targeting Δ-Valerolactone And Isocoumarin, Joshua Paul Van Houten
LSU Doctoral Dissertations
The purpose of this dissertation is to describe the efforts undertaken to develop synthetic methodology targeting δ-valerolactone and isocoumarin. At the onset, an introduction to the δ-valerolactone and isocoumarin is given. Relevant examples of δ-valerolactone being utilized in the production of materials of biological and industrial application are then discussed. Following, current methods for forming δ-valerolactone are presented. After, an introduction to isocoumarin is begun. Current methods for producing isocoumarin are then discussed.
The results and discussion section of this dissertation will focus on two methods that were explored with the goal of producing α-acyl-δ-valerolactone with two different substitution patterns. …