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Physical Sciences and Mathematics Commons

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Medicine and Health Sciences

Harrisburg University of Science and Technology

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Full-Text Articles in Physical Sciences and Mathematics

Speech Processing Approach For Diagnosing Dementia In An Early Stage, Roozbeh Sadeghian, J. David Schaffer, Stephen A. Zahorian Aug 2017

Speech Processing Approach For Diagnosing Dementia In An Early Stage, Roozbeh Sadeghian, J. David Schaffer, Stephen A. Zahorian

Faculty Works

The clinical diagnosis of Alzheimer’s disease and other dementias is very challenging, especially in the early stages. Our hypothesis is that any disease that affects particular brain regions involved in speech production and processing will also leave detectable finger prints in the speech. Computerized analysis of speech signals and computational linguistics have progressed to the point where an automatic speech analysis system is a promising approach for a low-cost non-invasive diagnostic tool for early detection of Alzheimer’s disease.

We present empirical evidence that strong discrimination between subjects with a diagnosis of probable Alzheimer’s versus matched normal controls can be achieved …


Towards An Automated Screening Tool For Pediatric Speech Delay, Roozbeh Sadeghian, Stephen A. Zahorian Sep 2015

Towards An Automated Screening Tool For Pediatric Speech Delay, Roozbeh Sadeghian, Stephen A. Zahorian

Faculty Works

Speech delay is a childhood language problem that sometimes is resolved on its own but sometimes may cause more serious language difficulties later. This leads therapists to screen children for detection at early ages in order to eliminate future problems. Using the Goldman-Fristoe Test of Articulation (GFTA) method, therapists listen to a child's pronunciation of certain phonemes and phoneme pairs in specified words and judge the child's stage of speech development. The goal of this paper is to develop an Automatic Speech Recognition (ASR) tool and related speech processing methods which emulate the knowledge of speech therapists. In this paper …