Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication
- File Type
Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
At Least Four Distinct Circadian Regulatory Mechanisms Required For All Phases Of Rhythms In Mrna Amount, Sigrid Jacobshagen, Bruce Kessler, Claire Rinehart
At Least Four Distinct Circadian Regulatory Mechanisms Required For All Phases Of Rhythms In Mrna Amount, Sigrid Jacobshagen, Bruce Kessler, Claire Rinehart
Mathematics Faculty Publications
Since the advent of techniques to investigate gene expression on a large scale, numerous circadian rhythms in mRNA abundance have been reported. These rhythms generally differ in amplitude and phase. First studies on circadian rhythms of transcription on a large scale are also emerging. We investigated to what extent the same circadian regulatory mechanism of transcription can give rise to rhythms in RNA amount that differ in phase solely based on a parameter that is not regulated by the circadian clock. Using a discrete-time approach, we modeled a sinusoidal rhythm in transcription with various constant exponential RNA decay rates. We …
Searching For Binding Partners For The Novel Phkg1 Variant, Phkγ 181, Kishore Polireddy
Searching For Binding Partners For The Novel Phkg1 Variant, Phkγ 181, Kishore Polireddy
Student Research Conference Select Presentations
Phopshorylase kinase (PhK) is a hexadecameric holoenzyme made up of four different subunits in the arrangement (αβγδ)4 and has total molecular mass of 1.3MDa. Alpha and β are regulatory subunits, γ is catalytic, and δ is an intrinsic molecule of calmodulin. PhK is a serine threonine kinase with glycogenolytic regulatory functions. Our lab has recently discovered that the γ subunit can be alternatively processed to produce a truncated form of 181 residues (γ-181). This variant of γ contains a phosphorylation site for PK-C, and its activity is influenced by this phosphorylation. We are using a LexA based yeast two hybrid …
38th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University
38th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University
Student Research Conference Select Presentations
Western Kentucky University 38th Annual Student Research Conference program and student abstracts. Saturday, April 12, 2008, Carroll Knicely Conference Center, Bowling Green, Kentucky.
Development And Recycling Of Novel Arsenic Removal Technology, Morgan Jones
Development And Recycling Of Novel Arsenic Removal Technology, Morgan Jones
Mahurin Honors College Capstone Experience/Thesis Projects
As of 2006, the U.S. Environmental Protection Agency (EPA) changed the Maximum Contaminant Level (MCL) for arsenic from 50 parts per billion (ppb), to 10ppb because of links to cancer. Current remediation technologies are expensive; therefore, this change will result in increased economic pressure on rural communities with high levels of arsenic in their drinking water. Lowering of the standard has spurred the development of a novel remediation technology that has shown the ability to reduce arsenic in drinking water at the source, with the added benefit of low-cost disposal of a stable and benign waste product in ordinary landfills. …