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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Life Sciences

Wayne State University

Series

2006

Articles 1 - 1 of 1

Full-Text Articles in Physical Sciences and Mathematics

Fm-Test: A Fuzzy-Set-Theory-Based Approach To Differential Gene Expression Data Analysis, Lily R. Liang, Shiyong Lu, Xuena Wang, Yi Lu, Vinay Mandal, Dorrelyn Patacsil, Deepak Kumar Jan 2006

Fm-Test: A Fuzzy-Set-Theory-Based Approach To Differential Gene Expression Data Analysis, Lily R. Liang, Shiyong Lu, Xuena Wang, Yi Lu, Vinay Mandal, Dorrelyn Patacsil, Deepak Kumar

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Microarray techniques have revolutionized genomic research by making it possible to monitor the expression of thousands of genes in parallel. As the amount of microarray data being produced is increasing at an exponential rate, there is a great demand for efficient and effective expression data analysis tools. Comparison of gene expression profiles of patients against those of normal counterpart people will enhance our understanding of a disease and identify leads for therapeutic intervention.

Results

In this paper, we propose an innovative approach, fuzzy membership test (FM-test), based on fuzzy set theory to identify disease associated genes from microarray …