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Full-Text Articles in Physical Sciences and Mathematics
Porphyrins And Porphyrin Applications, Derek Girouard
Porphyrins And Porphyrin Applications, Derek Girouard
Honors Theses
Porphyrins are a macrocyclic compound that can be modified in a myriad of ways offering useful and unique applications. These applications can range from ion sensing to catalysts in reactions. However, some of the most interesting applications revolve around medical and therapeutic treatments. Porphyrin derivatives can be used in processes known as photodynamic therapy (PDT) and photothermal therapy (PTT) to treat cancerous tumors. Porphyrins have been used in many ways in the body by their attachment to a variety of backbone structures. Porphyrins have potential to be widely utilized in therapeutic treatments as they are further studied and adapted to …
The Evolution Of Deuterium In The Pharmaceutical Industry And Its Effects On Methods Of Deuterium Incorporation, Angela Martinez
The Evolution Of Deuterium In The Pharmaceutical Industry And Its Effects On Methods Of Deuterium Incorporation, Angela Martinez
Honors Theses
The substitution of deuterium, an isotope of hydrogen containing one proton and one neutron, for a hydrogen has far reaching effects on the behavior of the compound. Scientists have been utilizing the effects of deuterium since 1961. The primary purpose for deuterium has been concentrated in the development of internal standards for NMR and mass spectrometers, due to their relative ‘silence’ in these studies, allowing scientists to elucidate mechanisms and trace a compound's movement throughout the body. However, recently, in addition to the use of deuterium as a standard, it has been added to developing or previously created pharmaceutical compounds …