Translational Medical Research Commons^™

Implantable Medical Devices For Local Drug Delivery And Tissue Regeneration To Combat Chronic Bacterial Infection, Caroline J. Billings

Doctoral Dissertations

Local drug delivery has been an area of exceptional interest in the treatment of chronic bacterial infections, particularly in areas where there are medical implants placed. Medical implants are widely utilized and are becoming increasingly popular with time. With the increasing use of medical implants, concomitant bacterial infection is also increasing, and this type of bacterial infection can be exceedingly difficult to clear. The following body of work focuses on implant-associated bacterial infection, with an emphasis on chronic Staphylococcus aureus (S. aureus) infection, particularly osteomyelitis. Specifically, this work is focused within the scope of utilizing locally implantable medical …