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Articles 1 - 30 of 211
Full-Text Articles in Translational Medical Research
Operative Versus Nonoperative Management For Diverticulitis Complicated By Abscess, Alix Bernholtz, Abbie R. Bauer
Operative Versus Nonoperative Management For Diverticulitis Complicated By Abscess, Alix Bernholtz, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
You K, Bendl R, Taut C, et al. Randomized clinical trial of elective resection versus observation in diverticulitis with extraluminal air or abscess initially managed conservatively. Br J Surg. 2018;105(8):971-979. https://doi.org/10.1002/bjs.10868
for a patient with a recurrent diverticulitis complicated by abscess formation.
Buprenorphine For Pain Management Vs. Chronic Hydrocodone-Acetaminophen Therapy When Comorbidities Increase The Risk Of Opioid-Related Side Effects, Jessica Zhao, Doo Hee Kim
Buprenorphine For Pain Management Vs. Chronic Hydrocodone-Acetaminophen Therapy When Comorbidities Increase The Risk Of Opioid-Related Side Effects, Jessica Zhao, Doo Hee Kim
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Gordon A, Callaghan D, Spink D, et al. Buprenorphine transdermal system in adults with chronic low back pain: a randomized, double-blind, placebo-controlled crossover study, followed by an open-label extension phase. Clin Ther. 2010;32(5):844-860. https://doi.org/10.1016/j.clinthera.2010.04.018
for a patient on long-term opioid therapy with high risk factors for adverse effects.
Simplifying Treatment From Double-Inhaler To Single-Inhaler Triple Therapy In Patients With Chronic Obstructive Pulmonary Disease, Kelly Yang, Leah Warren
Simplifying Treatment From Double-Inhaler To Single-Inhaler Triple Therapy In Patients With Chronic Obstructive Pulmonary Disease, Kelly Yang, Leah Warren
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using
Ferguson GT, Brown N, Compton C, et al. Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials. Respir Res. 2020;21(1):131. https://doi.org/10.1186/s12931-020-01360-w
for a patient requesting a simplified therapeutic regimen with equal efficacy for chronic obstructive pulmonary disease (COPD) management.
Effects Of Chaplain Care On Coping With Cancer, Sarah Battiston, Scott L. Baughan
Effects Of Chaplain Care On Coping With Cancer, Sarah Battiston, Scott L. Baughan
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical case decision report using:
Piderman KM, Radecki CR, Jenkins SM, et al. Hearing and heeding the voices of those with advanced illnesses. Journal of Palliative Care. 2020;35(4):248-255. https://doi.org/10.1177/0825859720928623
for a patient having difficulty coping with cancer
Efficacy Of Observational Care Versus Antibiotic Therapy For Treatment Of Acute Uncomplicated Diverticulitis, Morgan Mooty, Abbie R. Bauer
Efficacy Of Observational Care Versus Antibiotic Therapy For Treatment Of Acute Uncomplicated Diverticulitis, Morgan Mooty, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
van Dijk ST, Daniels L, Ünlü Ç, et al. Long-Term Effects of Omitting Antibiotics in Uncomplicated Acute Diverticulitis. Am J Gastroenterol. 2018;113(7):1045-1052. https://doi.org/10.1038/s41395-018-0030-y
for a patient with acute uncomplicated diverticulitis.
Radiofreqency Device As An Alternative Therapy For Refractory Nasal Valve Collapse, Sara Farooqui, Doo Hee Kim
Radiofreqency Device As An Alternative Therapy For Refractory Nasal Valve Collapse, Sara Farooqui, Doo Hee Kim
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using
Silvers SL, Rosenthal JN, McDuffie CM, Yen DM, Han JK. Temperature-controlled radiofrequency device treatment of the nasal valve for nasal airway obstruction: A randomized controlled trial. Int Forum Allergy Rhinol. 2021 Dec;11(12):1676-1684. http://doi.org/10.1002/alr.22861
for a patient with nasal valve collapse.
Safety And Cost Effectiveness Of Immediate Sequential Bilateral Cataracts Surgery, Miles Bowman, Abbie R. Bauer
Safety And Cost Effectiveness Of Immediate Sequential Bilateral Cataracts Surgery, Miles Bowman, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Rush SW, Gerald AE, Smith JC, Rush AJ, Rush RB. Prospective analysis of outcomes and economic factors of same-day bilateral cataract surgery in the United States. Journal of Cataract and Refractive Surgery. 2015;41(4):732-739. https://doi.org/10.1016/j.jcrs.2014.07.034
for a patient with bilateral cataracts.
Exploring The Neural Correlates Of Mindfulness-Based Interventions In Youth, Jovan Jande, Clara Zundel, Samantha Ely, Sneha Bhargava, Carmen Carpenter, Reem Tamimi, Leah Gowatch, Mackenna Shampine, Emilie-Clare O'Mara, Shravya Chanamolu, Hilary Marusak
Exploring The Neural Correlates Of Mindfulness-Based Interventions In Youth, Jovan Jande, Clara Zundel, Samantha Ely, Sneha Bhargava, Carmen Carpenter, Reem Tamimi, Leah Gowatch, Mackenna Shampine, Emilie-Clare O'Mara, Shravya Chanamolu, Hilary Marusak
Medical Student Research Symposium
Mindfulness based interventions (MBI) reduce the severity of anxiety and depression among a variety of populations. While the psychological benefits of MBIs are increasingly recognized, less is known about the underlying neural correlates—particularly during childhood and adolescence, a time when many psychopathologies begin to emerge. Here, we provide the first systematic review on the neural correlates of MBI in youth. We reviewed the PubMed database for original articles examining the neural correlates of MBI in youth (0-18 years) leveraging neuroimaging. The search yielded 331 studies, of which 13 were included in the review. These studies comprised 451 participants and were …
Lack Of Alternatives To Colonoscopy Limits Care Of Patients Unable To Complete Bowel Preparation, Tala Al-Saghir
Lack Of Alternatives To Colonoscopy Limits Care Of Patients Unable To Complete Bowel Preparation, Tala Al-Saghir
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Benech N, Vinet O, Gaudin JL, et al.: The ONECC Study Group. Colon capsule endoscopy in clinical practice: lessons from a national 5-year observational prospective cohort. Endosc Int Open. 2021;9(10):E1542-E1548. https://doi.org/10.1055/a-1526-09231
for a patient with incomplete bowel preparation and colonoscopy.
Multiple Daily Injection Insulin Regimen Is An Effective, And More Economical, Alternative To Continuous Insulin Infusion For Type 1 Diabetics, Julia Yee
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Heller S, White D, Lee E, et al. A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technol Assess. 2017 Apr;21(20):1-278. https://doi.org/10.3310/hta21200
for a patient with type 1 diabetes.
An American Medical Economics Phenomenon, Richard Guthmann Md, Mph
An American Medical Economics Phenomenon, Richard Guthmann Md, Mph
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on his own experience with medical economics-driven phenomena in healthcare.
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients, Abigail C. Kuplicki
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients, Abigail C. Kuplicki
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Moriarty PM, Thompson PD, Cannon CP, et al. Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial. J. Clin. Lipidol. 2015;9(6):758-769. https://doi.org/10.1016/j.jacl.2015.08.006
for a statin-intolerant patient with hyperlipidemia.
Renal Disease Rehabilitation And Delaying Dialysis, Spencer Brown, Natalie Sterner
Renal Disease Rehabilitation And Delaying Dialysis, Spencer Brown, Natalie Sterner
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Greenwood SA, Koufaki P, Mercer TH, et al. Effect of exercise training on estimated GFR, vascular health, and cardiorespiratory fitness in patients with CKD: a pilot randomized controlled trial. Am J Kidney Dis. 2015;65(3):425-434. https://doi.org/10.1053/j.ajkd.2014.07.015
for a patient with non-dialysis CKD interested in slowing the progression toward necessary dialysis.
Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi
Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi
Clinical Research in Practice: The Journal of Team Hippocrates
Reflection on how delayed colostomy reversal affects a patient's mental and physical well-being.
Uptitrating Mycophenolate Mofetil Therapy In A Patient With Lupus Cerebritis Doesn’T Increase Risk Of Infection Compared To Cyclophosphamide, Gautham Pavar
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report appraising
Appel GB, Contreras G, Dooley MA, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol. 2009;20(5):1103-1112. https://doi.org/10.1681/ASN.2008101028
for a patient with neuropsychiatric lupus.
Stigma And Patient-Controlled Analgesia: Trust Is The Essential Ingredient Of Successful Patient Education In The Patient-Doctor Relationship, Trey D. Vanaken
Stigma And Patient-Controlled Analgesia: Trust Is The Essential Ingredient Of Successful Patient Education In The Patient-Doctor Relationship, Trey D. Vanaken
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Van Beers EJ, Van Tuijn CFJ, Nieuwkerk PT, et al. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol. 2007;82(11):955-960. https://doi.org/10.1002/ajh.20944.
for a patient with recurrent vaso-occlusive crisis secondary to Sickle Cell Disease.
Early Closure Of Colostomy From Abdominal Trauma May Be Beneficial In Otherwise Healthy Patients, Nicole Xu
Early Closure Of Colostomy From Abdominal Trauma May Be Beneficial In Otherwise Healthy Patients, Nicole Xu
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report appraising
Khalid MS, Moeen S, Khan AW, Arshad R, Khan AF. Same admission colostomy closure: a prospective, randomised study in selected patient groups. Surgeon. 2005;3(1):11-14. https://doi.org/10.1016/s1479-666x(05)80004-6
for a patient with loop transverse colostomy due to trauma
Evaluating The Use Of Cheaper, Less Effective Medications In Patients With Cost-Based Medication Nonadherence, Muneer F. Hasso
Evaluating The Use Of Cheaper, Less Effective Medications In Patients With Cost-Based Medication Nonadherence, Muneer F. Hasso
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Sangaralingham LR, Sangaralingham SJ, Shah ND, Yao X, Dunlay SM. Adoption of Sacubitril/Valsartan for the Management of Patients With Heart Failure. Circ Heart Fail. 2018;11(2):e004302. https://doi.org/10.1161/circheartfailure.117.004302
for a patient with low medication adherence rates due to the high out-of-pocket costs of newer medications.
Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan
Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Gagneur A, Lemaître T, Gosselin V, et al. A postpartum vaccination promotion intervention using motivational interviewing techniques improves short-term vaccine coverage: PromoVac study. BMC public health. 2018;18(1):811. https://doi.org/10.1186/s12889-018-5724-y
for a juvenile patient with a caregiver who is skeptical about the safety of routine vaccinations.
Buprenorphine/Suboxone Is Safe In Pregnancy: Substance Use And Stigma In The Healthcare Professions, Blake S. Sanford
Buprenorphine/Suboxone Is Safe In Pregnancy: Substance Use And Stigma In The Healthcare Professions, Blake S. Sanford
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Mullins N, Galvin SL, Ramage M, et al. Buprenorphine and Naloxone Versus Buprenorphine for Opioid Use Disorder in Pregnancy: A Cohort Study. J Addict Med. 2020;14(3):185-192. https://doi.org/10.1097/ADM.0000000000000562
for a woman with opioid use disorder during pregnancy.
Flexner Report 3.0—Structurally Competent Healthcare, James Peter Meza
Flexner Report 3.0—Structurally Competent Healthcare, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The editor advocates to formalize the addition of “Medical Social Sciences” as a basic science in our Schools of Medicine and “Clinical Decision Science” as the corollary clinical practice discipline: a “Flexner Report 3.0."
Professionalism And Moral Injury In A Capitalist Healthcare System, James Peter Meza Md, Phd, Kassem Soufan Md, Michael Francis Do, Abbass Berjaoui Md
Professionalism And Moral Injury In A Capitalist Healthcare System, James Peter Meza Md, Phd, Kassem Soufan Md, Michael Francis Do, Abbass Berjaoui Md
Clinical Research in Practice: The Journal of Team Hippocrates
Professionalism cautions against profit while capitalism exists for profit. This case is a structural analysis of capitalism in a clinical setting that reveals physicians to be simultaneously wage laborers and professionals. Capitalism generates profit. Professionalism views profit as a conflict of interest that erodes trust in the doctor-patient relationship. Managing these conflicting values causes moral injury for physicians, which is a driver of physician burnout.
Mechanical Thrombectomy For Intermediate Risk Pulmonary Embolism, James Peter Meza, Marissa Costello Md, Angela Moughni Md, Nicholus Yee Md
Mechanical Thrombectomy For Intermediate Risk Pulmonary Embolism, James Peter Meza, Marissa Costello Md, Angela Moughni Md, Nicholus Yee Md
Clinical Research in Practice: The Journal of Team Hippocrates
An informed consent article using a set of publications to develop an informed consent conversation for a patient with an acute pulmonary embolism being considered for pulmonary artery thrombolysis.
I Finally Understand How Applying The Fagan Nomogram Can Change Medical Decision-Making, David Salvatori, Do
I Finally Understand How Applying The Fagan Nomogram Can Change Medical Decision-Making, David Salvatori, Do
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on the case that changed his opinion on the efficacy of the Fagan nomogram.
Thymic Stromal Lymphopoietin Participates In The Host Response To Intra-Amniotic Inflammation Leading To Preterm Labor And Birth, Tomi Kanninen, Li Tao, Roberto Romero, Yi Xu, Marcia Arenas-Hernandez, Jose Galaz, Zhenjie Liu, Derek Miller, Dustyn Levenson, Jonathan M. Greenberg, Jonathan Panzer, Justin Padron, Kevin Theis, Nardhy Gomez-Lopez Phd
Thymic Stromal Lymphopoietin Participates In The Host Response To Intra-Amniotic Inflammation Leading To Preterm Labor And Birth, Tomi Kanninen, Li Tao, Roberto Romero, Yi Xu, Marcia Arenas-Hernandez, Jose Galaz, Zhenjie Liu, Derek Miller, Dustyn Levenson, Jonathan M. Greenberg, Jonathan Panzer, Justin Padron, Kevin Theis, Nardhy Gomez-Lopez Phd
Medical Student Research Symposium
Objective: To determine if bacteria (Ureaplasma parvum and Sneathia spp.) associated with intra-amniotic infection can trigger the induction of cytokine Thymic stromal lymphopoietin (TSLP) in human amnion epithelial cells (hAECs) in vitro.
Material or subjects: Amniotic fluid and chorioamniotic membrane (CAM) were collected from women with sPTL who delivered at term (n=30) or preterm without intra-amniotic inflammation (n=34), with sterile intra-amniotic inflammation (SIAI, n=27), or with intra-amniotic infection (IAI, n=17). Amnion epithelial cells (AECs), Ureaplasma parvum, and Sneathia spp. were also utilized.
Methods: The expression of TSLP, TSLPR, and IL-7Rα was evaluated in amniotic fluid or CAM by …
Implicit Bias And Stigma Theory In Clinical Practice: Developing “Habits Of Mind” For Clinical Inquiry, James Peter Meza
Implicit Bias And Stigma Theory In Clinical Practice: Developing “Habits Of Mind” For Clinical Inquiry, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The editor introduces a new article type in this issue, Translational Social Science, and reflects on the social theory required to perceive and counteract implicit bias.
Stigma Is A Very Real Part Of Clinical Practice, Aaron Rivkin
Stigma Is A Very Real Part Of Clinical Practice, Aaron Rivkin
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on avoiding stigmatizing language in clinical practice.
Bioprosthetic Reoperative Aortic Valve Replacement In Patients Under 50, Aisha Kazeem
Bioprosthetic Reoperative Aortic Valve Replacement In Patients Under 50, Aisha Kazeem
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Chan V, Lam BK, Rubens FD, et al. Long-term evaluation of biological versus mechanical prosthesis use at reoperative aortic valve replacement. J Thorac Cardiovasc Surg. 2012;144(1):146-151. https://doi.org/10.1016/j.jtcvs.2011.08.041
for a patient considering reoperative aortic valve replacement.
Renal Replacement Therapy Could Be Initiated In Patients With Severe Aki, Regardless Of Age And Critical Condition, El Hussain Shamsa
Renal Replacement Therapy Could Be Initiated In Patients With Severe Aki, Regardless Of Age And Critical Condition, El Hussain Shamsa
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Meersch M, Küllmar M, Schmidt C, et al. Long-Term Clinical Outcomes after Early Initiation of RRT in Critically Ill Patients with AKI. J Am Soc Nephrol. Mar 2018;29(3):1011-1019. https://doi.org/10.1681/asn.2017060694
for a critically ill elderly patient with severe acute kidney injury.
The Effect Of Medical Respite Services On Hospital Readmissions For Those Experiencing Homelessness, Kendrick Belardo
The Effect Of Medical Respite Services On Hospital Readmissions For Those Experiencing Homelessness, Kendrick Belardo
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Kertesz SG, Posner MA, O’Connell JJ, et al. Post-Hospital Medical Respite Care and Hospital Readmission of Homeless Persons. J Prev Interv Community. 2009;37(2):129-142. https://doi.org/10.1080/10852350902735734
for a patient experiencing homelessness.