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Translational Medical Research Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Translational Medical Research
Translational Research: Ethical Considerations, Yiqing Dong
Translational Research: Ethical Considerations, Yiqing Dong
Honors Program Theses
Translational research (TR) is a new categorization for the efforts of biomedical research and emphasizes efficiency in achieving population health improvements through the application of basic science knowledge in clinical practice. It will be argued that the current emphasis on speed and collaboration with industry established by national policies provides challenges to maintaining the integrity of scientific research. There is no agreed upon definition of TR and the current standard of judging the success of TR focuses on product production. I propose that the principles of beneficence and responsive justice should be used to inform the values of TR and …
Translational Research: Ethical Considerations, Yiqing Dong
Translational Research: Ethical Considerations, Yiqing Dong
Sound Decisions: An Undergraduate Bioethics Journal
Translational research (TR) is a new categorization for the efforts of biomedical research and emphasizes efficiency in achieving population health improvements through the application of basic science knowledge in clinical practice. It will be argued that the current emphasis on speed and collaboration with industry established by national policies provides challenges to maintaining the integrity of scientific research. There is no agreed upon definition of TR and the current standard of judging the success of TR focuses on product production. I propose that the principles of beneficence and responsive justice should be used to inform the values of TR and …
The Role Of Mmp9 In Satellite Cell Activation After Increased Activity, Mike H.M.H. Pang, Jung A. Kim, Gary E. Mccall, Ryan S. Mehan, J-P Hyatt
The Role Of Mmp9 In Satellite Cell Activation After Increased Activity, Mike H.M.H. Pang, Jung A. Kim, Gary E. Mccall, Ryan S. Mehan, J-P Hyatt
Summer Research
The unique adaptive ability of skeletal muscle to meet functional demands is exemplified in its response to exercise. Though little is known about the molecular mechanisms that regulate this plasticity, the extracellular matrix (ECM) is believed to play a large role. The basal lamina is a specialized layer of ECM that lies in direct contact with the cell membrane of muscle fibers and facilitates environment-to-cell interactions. Matrix metalloproteinase-9 (MMP-9) is an enzyme in the basal lamina that regulates much of these adaptive processes. During exercise, the regenerative process of damaged tissue requires the activation of muscle-specific stem cells known as …