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Translational Medical Research Commons™
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Articles 1 - 24 of 24
Full-Text Articles in Translational Medical Research
Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza
Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The Faculty Editor advocates for the training of clinician scientists again, using the body of clinical research as the laboratory.
Earth Suit, Bowhee Gwak, Young Park
Earth Suit, Bowhee Gwak, Young Park
Clinical Research in Practice: The Journal of Team Hippocrates
The authors reflect on an experience learning at the feet of a spirited patient.
Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet
Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet
Clinical Research in Practice: The Journal of Team Hippocrates
A fumbling attempt at critical analysis in support of a clinical decision crystallizes the author's understanding that skillful analysis of research is crucial to good practice.
Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler
Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Manzardo C, Esteve A, Ortega N, et al. Optimal timing for initiation of highly active antiretroviral therapy in treatment-naïve human immunodeficiency virus-1-infected individuals presenting with AIDS-defining diseases: the experience of the PISCIS Cohort. Clin. Microbiol. Infect. 2013 July;19(7):646-653. doi: 10.1111/j.1469-0691.2012.03991.x
Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong
Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Bart BA, Goldsmith SR, Lee KL et al. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. N Engl J Med. 2012;367:2296-2304. doi: 10.1056/NEJMoa1210357
Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson
Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Li M, Law SW, Cheng J, Kee HM, Wong MS. A comparison study on the efficacy of SpinoMed® and soft lumbar orthosis for osteoporotic vertebral fracture. J. Prosthet. Orthot. Int. 2015;39(4):270-276. doi: 10.1177/0309364614528204
Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers
Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Sengupta N, Feuerstein JD, Patwardhan VR, et al. The risks of thromboembolism vs. recurrent gastrointestinal bleeding after interruption of systemic anticoagulation in hospitalized in patients with gastrointestinal bleeding: a prospective study. Am. J. Gastroenterol. 2014;110:328-335. doi: 10.1038/ajg.2014.398
Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D.
Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D.
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Travers B, O’Loughlin C, Murphy NF, et al. Fluid restriction in the management of decompensated heart failure: no impact on time to clinical stability. J Card Fail. 2007;13(2):128-132. doi: 10.1016/j.cardfail.2006.10.012
Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor
Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Shelton E, Allegretti J, Stevens B et al. Efficacy of Vedolizumab as Induction Therapy in Refractory IBD Patients. Inflammatory Bowel Diseases. 2015 Dec;21(12):2879-2885. doi:10.1097/mib.0000000000000561
Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong
Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet. 2002;360(9346):1623-30. doi:10.1016/S0140-6736(02)11600-X
It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane
It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Esrailian E, Pantangco ER, Kyulo NL, Hu KQ, Runyon BA. Octreotide/midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome. Dig Dis Sci. 2007;52(3):742-748. doi: 10.1007/s10620-006-9312-0
Salvage Therapy For Non-Acetaminophen-Induced Acute Liver Failure Includes N-Acetylcysteine, David Robinson
Salvage Therapy For Non-Acetaminophen-Induced Acute Liver Failure Includes N-Acetylcysteine, David Robinson
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Lee WM, Hynan LS, Rossaro L, et al. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Gastroenterology. 2009;137(3):856-864. doi: 10.1053/j.gastro.2009.06.006
From The Editors, Thomas C. Bolig, William Kane, Mitchell Kentor
From The Editors, Thomas C. Bolig, William Kane, Mitchell Kentor
Clinical Research in Practice: The Journal of Team Hippocrates
Introduction to Volume 2, Issue 2 by the new Senior Student Editors.
Guidelines Are Not Evidence, James P. Meza Md, Phd, Nicholus H. Yee Md
Guidelines Are Not Evidence, James P. Meza Md, Phd, Nicholus H. Yee Md
Clinical Research in Practice: The Journal of Team Hippocrates
Guidelines are inherently flawed when caring for an individual patient, because they apply to populations, not individuals. A strong competency in reading and interpreting clinical research gives doctors the power to evaluate guidelines and make appropriate shared decisions with their patients.
There Is Relief For Constipated Patients Taking Opioids., Ahmad Mohammadieh, James Choi, Md, Chelsea Gonzalez, Do, Diyanah Elyaman, Md
There Is Relief For Constipated Patients Taking Opioids., Ahmad Mohammadieh, James Choi, Md, Chelsea Gonzalez, Do, Diyanah Elyaman, Md
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Tack J, Lappalainen J, Diva U, Tummala R, Sostek M. Efficacy and safety of naloxegol in patients with opioid-induced constipation and laxative-inadequate response. United European Gastroenterol J. 2015 Oct;3(5):471-80. doi: 10.1177/2050640615604543
Carotid Ultrasound Is Not Helpful In Simple Syncope, Nicholus Yee M.D., Shilin Patel M.D., Raymond Gong
Carotid Ultrasound Is Not Helpful In Simple Syncope, Nicholus Yee M.D., Shilin Patel M.D., Raymond Gong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Scott JW, Schwartz AL, Gates JD, Gerhard-Herman M, Havens JM. Choosing wisely for syncope: low-value carotid ultrasound use. J Am Heart Assoc. 2014 Aug 13;3(4). pii: e001063. doi: 10.1161/JAHA.114.001063
Viruses, Vaccines And The Public, Judy Diamond, Julia Mcquillan, Amy Spiegel, Patricia Wonch Hill, Rebecca Smith, John T. West, Charles Wood
Viruses, Vaccines And The Public, Judy Diamond, Julia Mcquillan, Amy Spiegel, Patricia Wonch Hill, Rebecca Smith, John T. West, Charles Wood
World of Viruses
Current research in virology is changing public conceptions about vaccines and infectious disease. The University of Nebraska State Museum collaborated with research virologists, science writers, artists and learning researchers to create public outreach materials about viruses and infectious disease. The project, funded by the National Institute of Health’s SEPA program, developed comics, a book with Carl Zimmer, and other materials and programs. The project launched three kinds of learning research: 1) a survey of Nebraska adults on their opinions about vaccines and infectious disease; 2) a study comparing the mental models of viruses, vaccines and infection from virologists, teachers, and …
Advocating For Our Patients Using Clinical Research, Brandon Baker
Advocating For Our Patients Using Clinical Research, Brandon Baker
Clinical Research in Practice: The Journal of Team Hippocrates
This reflection is about experiences trying to relate medical research evidence to actual patient care. This piece talks about shared decision-making about screening mammography.
Splenic Biopsies Are Underutilized Due To Overestimation Of Bleeding Risks, Nicholas Destefano
Splenic Biopsies Are Underutilized Due To Overestimation Of Bleeding Risks, Nicholas Destefano
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Civardi G, Vallisa D, Berte R, et al. Ultrasound-guided fine needle biopsy of the spleen: high clinical efficacy and low risk in a multicenter Italian study. Am J Hematol. 2001 Jun;67(2):93-9. doi:10.1002/ajh.1085
Attitudes Toward Substance Abuse Clients: An Empirical Study Of Clinical Psychology Trainees, Chandra Mundon, Melissa Anderson, Lisa Najavits
Attitudes Toward Substance Abuse Clients: An Empirical Study Of Clinical Psychology Trainees, Chandra Mundon, Melissa Anderson, Lisa Najavits
Melissa L. Anderson
Despite the high prevalence of substance use disorder (SUD) and its frequent comorbidity with mental illness, individuals with SUD are less likely to receive effective SUD treatment from mental health practitioners than SUD counselors. Limited competence and interest in treating this clinical population are likely influenced by a lack of formal training in SUD treatment. Using a factorial survey-vignette design that included three clinical vignettes and a supplementary survey instrument, we investigated whether clinical psychology doctoral students differ in their level of negative emotional reactions toward clients with SUD versus major depressive disorder (MDD); whether they differ in their attributions …
Abnormal Uterine Bleeding Guidelines And Clinical Practice Are Based On Poor Quality Evidence, Mirek Mychajlowycz
Abnormal Uterine Bleeding Guidelines And Clinical Practice Are Based On Poor Quality Evidence, Mirek Mychajlowycz
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Munro MG, Mainor N, Basu R, Brisinger M, Barreda L. Oral medroxyprogesterone acetate and combination oral contraceptives for acute uterine bleeding: A randomized controlled trial. Obstet Gynecol. 2006 Oct;108(4):924-929. doi:10.1097/01.AOG.0000238343.62063.22
Induced Hypothermia Post Cardiac Resuscitation Works In Hospitalized Patients But Not During Transport To Hospital, A Logical Inconsistency Of Evidence, Joshua Frederick
Induced Hypothermia Post Cardiac Resuscitation Works In Hospitalized Patients But Not During Transport To Hospital, A Logical Inconsistency Of Evidence, Joshua Frederick
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Kim F, Nichol G, Maynard C, et al. Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest. JAMA 2013;311(1):45-52. doi:10.1001/jama.2013.282173
Defining Quality In Medical Practice, Nicholas E. Boggs
Defining Quality In Medical Practice, Nicholas E. Boggs
Clinical Research in Practice: The Journal of Team Hippocrates
We need physicians who are willing to participate in creating the standard of care, and to hold insurance companies accountable for real evidence-based quality markers. Only then will patients receive adequate care and we as educators in medicine be able to adequately teach the next generation of physicians.
From The Editors, John Dawdy, J. Timothy Caldwell
From The Editors, John Dawdy, J. Timothy Caldwell
Clinical Research in Practice: The Journal of Team Hippocrates
Editorial introduction to the third issue of Clinical Research in Practice: The Journal of Team Hippocrates.