Sports Sciences Commons^™

The Hemostatic Effects Of Acute Exposure To Colored Cornstarch Powder During A 5k Run, Robert C. Allsbrook

Senior Honors Projects, 2010-2019

PURPOSE: To examine the acute hemostatic effects of particulate matter (PM) in the form of colored corn starch powder during a 5 kilometer race. METHODS: 10 recreationally active adults completed two 5k runs, one with color and one without color. 10 mL blood samples were taken 6 hours prior to the trial and immediately following the trial. PAI-1 activity, FVIII antigen, and tPA activity were measured using an ELISA. RESULTS: No significant main effects or interaction effects (P<0.05) were observed among any of the variables although a trend (P = 0.082) was observed for increased PAI-1 activity during exercise in the color condition. CONCLUSIONS: There is a trend towards increased PAI-1 activity levels during exercise during color runs that could be due to increased inflammation. Furthermore, the lack of increased FVIII:ag and tPA activity suggests that the intensity of the exercise may not have been adequate and further research should be conducted in this area.

Caffeine Mouth Rinsing In The Fed State Does Not Enhance 3-Km Cycling Performance In The Morning Or Evening, Kayla Sweeney

Senior Honors Projects, 2010-2019

PURPOSE: To assess the effect of a caffeine mouth rinse on performance at different times of day. METHODS: 12 recreational cyclists completed a simulated 3-km time trial and 4 sets of 5 leg extension repetitions, twice in the morning and twice in the evening. 25 ml of 1.14% caffeine, or placebo solution was mouth rinsed before sets 3 and 4 of the leg extension and before the time trial. Treatments include: caffeine + morning, placebo + morning, caffeine + evening, and placebo + evening. RESULTS: The caffeine rinse had a negative impact on time trial performance in both the morning …

Hemostatic Responses To Exercise In A Polycythemia Vera Patient, Allison M. Huschke

Senior Honors Projects, 2010-2019

PURPOSE: To assess the hemostatic responses to exercise in a patient with Polycythemia Vera (PV). METHODS: Six female runners (≥15 miles/week) completed a maximal treadmill test. One subject had PV while the other five subjects made up the comparison group. Blood samples were taken before and within two minutes after exercise. VO2max was also recorded. RESULTS: Pre-exercise Factor VIII and tPA-antigen were similar in the PV subject and comparison group. Factor VIII and tPA-antigen increased dramatically in the PV subject (+100%, +1000%) in relation to the comparison group (+22.9 ± 8.7%, +108 ± 78%) after exercise. Pre-exercise PAI-1 was lower …

Macronutrient Supplementation For Endurance Athletes, Jonathan B. Hurst

Senior Honors Projects, 2010-2019

Purpose: The present study addressed two questions related to macronutrient supplementation during endurance exercise. Firstly, the effects of carbohydrate and protein co-ingestion on time trial (TT) performance were compared to carbohydrate alone. Secondly, the effects of isolated protein ingestion on TT performance were compared to a placebo.

Methods: Six trained cyclists (Age: 22 ± 1 years; Height: 167 ± 12 cm; Weight: 60 ± 10 kg; VO_2max: 62 ± 7 ml/kg/min) completed four experimental trials, consisting of constant-load cycling for two hours (55% W_max) immediately followed by a 30-km simulated time trial. During the trials, subjects …

Brain Derived Neurotrophic Factor Response During Endurance Cycle Training: Impact Of Carbohydrate And Protein Supplementation, Jordan L. Parker

Senior Honors Projects, 2010-2019

Purpose: Brain Derived Neurotrophic Factor (BDNF) is part of the superfamily of neurotrophins including: nerve growth factor (NGF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4). Recent evidence suggests that aerobic activity can increase BDNF levels both during and following exercise. Likewise, dietary habits have been shown to alter BDNF levels. However, nothing is known about the effect of BDNF levels during aerobic activity under specific dietary interventions. The purpose of this study was to examine the effects of specific macronutrient supplementation on BDNF levels during aerobic exercise. Methods: We had the opportunity to determine BDNF levels in blood samples obtained from two …