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Imitation In Fragile X Syndrome: Implications For Autism, Marta Macedoni-Luksic, Laura Greiss Hess, Sally J. Rogers, David Gosar, Kerrie Lemons-Chitwood, Randi Hagerman

Occupational Therapy | Faculty Scholarship

To address the specific impairment of imitation in autism, the imitation abilities of 22 children with fragile X syndrome (FXS) with and without autism were compared. Based on previous research, we predicted that children with FXS and autism would have significantly more difficulty with non-meaningful imitation tasks. After controlling for full-scale IQ and age, the groups did not differ in their overall imitation accuracy scores, but analysis of error patterns revealed that children with FXS and autism made more groping errors and additional movements than the comparison group. These error patterns are consistent with the hypothesis that an action production …

Motor Abilities Of Children Diagnosed With Fragile X Syndrome With And Without Autism, C. Zingerevich, L. G. Hess, K. Lemons Chitwood, S. W. Harris, D. Hessl, K. Cook, R. J. Hagerman

Collected Faculty and Staff Scholarship

Background—Previous studies suggested that children diagnosed with Fragile X Syndrome (FXS) often meet criteria for autism or PDD. This study describes the fine motor abilities of children diagnosed with FXS with and without autism spectrum disorder, and compares the motor scores of those groups controlling for cognitive level.

Method—Forty-eight children, ages 12-76 months (SD=16) diagnosed with FXS were assessed with the Mullen Scales of Early Learning, and the Autism Diagnostic Observation Schedule (ADOS). Their parents were interviewed with the Autism Diagnostic Interview-Revised (ADI-R). We used a one-way analysis of variance (ANOVA) to determine if the fine motor scale …